Scotty, you shouldnt be having a back up of bile into your stomach. If you do then there is a problem because bile is excreted after your stomach. You could more likely just have occasional gastritis. In that case, yes carafate will help. Personally I have had the same problem. I get intermittent pain when my stomach is empty and it will come for a few weeks and then leave for a while. I discovered that if i take tums the pain goes away. Then I could get away with not having to take regular medication. But yes carafate may help you. I personally found that the liquid carafate, which is more expensive, worked better than the slurry pills. This might be a silly question, but did you try just pepto when this happens?