Re: prednisone and hiccup type spasms
You posted some time ago, so don't know if you're still around or will see this. I don't frequent this Board much but just came across your post.
Intractable hiccups can be devastating indeed. They are believed to be caused mainly by irritation of either the phrenic or vagus nerves anywhere along their paths.
Central nervous system diseases, toxins, drugs and metabolic abnormalities may also lead to hiccups.
Hiccups lasting longer than two days are termed "persistent" and those lasting longer than one month are considered "intractable.".
Given that the doctors have performed numerous tests to rule out serious underlying disease, has your fiance been given any medications to try?
Many pharmacologic and (nonpharmacologic remedies) have been used to try to abort hiccups. Medications that have been reported to be effective include chlorpromazine (Thorazine), nifedipine (Procardia), haloperidol (Haldol), phenytoin (Dilantin), metoclopramide (Reglan), baclofen (Lioresal) and gabapentin (Neurontin).
As a last resort, there is surgical management, which includes such techniques as phrenic nerve interruption or placement of diaphragmatic pacemakers. has this been discussed as an option?