NSAIDs - Drug Interactions / Side Effects Message Board

PerfectDay · 07-31-2005, 04:40 AM

Does anyone know much about NSAIDs (Nonsteroidal Anti-Inflammatory Drugs)? Just was wondering if anybody knew which of the drugs are COX1 enzyme selective, COX2 enzyme selective or non-selective. Any info would be great thanks!

GLSheridan · 08-02-2005, 09:01 AM

Quote:

Originally Posted by PerfectDay

Does anyone know much about NSAIDs (Nonsteroidal Anti-Inflammatory Drugs)? Just was wondering if anybody knew which of the drugs are COX1 enzyme selective, COX2 enzyme selective or non-selective. Any info would be great thanks!

Here's what I know:

COX1 selective group
low dose aspirin

COX1 non-selective group
high dose aspirin
Voltaren (diclofenac)
Motrin (ibuprofen)
Indocin (indomethacin)
Ponstel (mefenamic acid)
Naprosyn (naproxen)
Feldene (piroxicam)

COX2 selective group
Toradol (ketorolac)
Mobic (meloxicam)
Relafen (nabumetone)

COX2 highly selective group
Celebrex (celicoxib)