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Old 11-08-2007, 10:39 PM   #1
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PPI side effects

Hi everyone,
I really need to be taking a proton pump inhibitor. Unfortunately, they cause me to have spasms in my throat. I have tried Nexium and Prilosec and maybe something else. And after a few days I start gettng throat spasms which scare me and I stop the meds. Has anyone had this weird side effect? I really need to be taking a ppi but don't know what to do. Should I keep trying all the various brands? Other types of anti-acids (not the ppis) don't seem to do the job. I usually never take any allopathic meds at all. But I really need to get my acid under control because it's causing me horrible mucus issues. Has anyone found a natural alternative that works just as well (some herbal formula, etc.) ?

 
Old 11-10-2007, 06:29 AM   #2
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Re: PPI side effects

Hello,
Can u describe what u mean by spasms in your throat. Does it hamper
your breathing at all, I think I may experienced something similiar, I have severe gerd, acid reflux or all of the above. I was taking aciphex and had
a terrible reaction to it after taking it for about 8 months. Let me know.
sea




Quote:
Originally Posted by stardust11 View Post
Hi everyone,
I really need to be taking a proton pump inhibitor. Unfortunately, they cause me to have spasms in my throat. I have tried Nexium and Prilosec and maybe something else. And after a few days I start gettng throat spasms which scare me and I stop the meds. Has anyone had this weird side effect? I really need to be taking a ppi but don't know what to do. Should I keep trying all the various brands? Other types of anti-acids (not the ppis) don't seem to do the job. I usually never take any allopathic meds at all. But I really need to get my acid under control because it's causing me horrible mucus issues. Has anyone found a natural alternative that works just as well (some herbal formula, etc.) ?

 
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Old 11-12-2007, 03:33 AM   #3
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Re: PPI side effects

yes please describe more I may have had that to on a ppi.

 
Old 11-13-2007, 02:09 AM   #4
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Re: PPI side effects

Hello all.
My only symptoms from GERD are the severe reflux burning in my chest and throat, no spasms or stomach pain. I used to wake up at night choking also from the reflux in my throat, but now that I use a slanted elevated pillow, major improvement now. My GERD started about 10 years ago, was on Prilosec 9 of the 10 years and now Nexium about a year with no problems. I'm going to try ginger tea and licorice extract. I've heard the probiotics like yogurt are good too. One day I want to get off PPIs completely because I'm concerned about their negative long term use.
Amber

 
Old 11-13-2007, 07:55 PM   #5
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Re: PPI side effects

amber,

my doctor just told me to use 2x4s to raise my bed. He says it will help stop the reflux from coming up into my throat at night & causing me to choke. I think I'll try some plywood, maybe a couple of sheets or so under the upper part of the mattress. I tried sleeping on several pillows but it didn't help much plus I can't sleep that way. Last night was the worst one ever. I got no more than a couple of hours of interrupted sleep. The acid coming up makes me feel as if I am drowning. I hope to get more sleep tonight. I am so tired...

 
Old 11-13-2007, 08:18 PM   #6
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Re: PPI side effects

Hi Everyone,
for me, after a couple of days on any PPI I get throat spasms. It's as if I can feel the sphincter/muscle contracting quickly. And like I wasn't breathing for a few seconds/had to catch my breath. It's weird because PPIs are supposed to cure these things, not cause them. When I tried to explain this to drs, they didn't believe me because it's not listed as one of its side effect. So I don't know what to do. Has anyone else experienced esophagus spasms from PPIs? If i thought that it was a good reaction and healing something, then I'd keep taking it. But it feels very scary so I don't take them right now.

 
Old 11-13-2007, 10:08 PM   #7
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Re: PPI side effects

I was doing some reading and these muscle spasms may be caused by faulty calcium metabolism and associated with diminished function of the parathyroid glands. So maybe the PPIs are upsetting the calcium balance in the stomach. Maybe they're depleting magnesium levels. I wonder if something like Tri-Salts by Ecological Formulas would help restore the balance. Or maybe some other natural supplement. I've tried Tri-Salts for a couple days so far. I have symptoms of Laryngopharyngeal reflux and I don't know if this is powerful enough to help with that. But it is said to neutralize increased acidity.

Last edited by stardust11; 11-14-2007 at 10:08 AM.

 
Old 11-13-2007, 10:36 PM   #8
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Re: PPI side effects

I agree , I have found PPI's cause weight gain-
Just as SSRI'S do-

 
Old 11-14-2007, 11:17 PM   #9
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Re: PPI side effects

Thank you for the information, Stardust!

The muscle spasms are extremely painful and scary. I had mine happen in the upper abdominal area, not throat, with a bulge present. Totally creepy. I suspected the hiatal hernia. The doctor said no big deal, eveyone gets them. Not the type I had!!! They remain unexplained. I do know that electrolyte deficiencies can cause spasms. I take calcium & magnesium supplements. I am on a sodium restrictive diet, so who knows if a temporary low sodium level might have caused them.

flowergirl

 
Old 11-14-2007, 11:42 PM   #10
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Re: PPI side effects

Hi flowergirl2day
Yeah, in the body Calcium, Sodium and Potassium have to be in proper balance.

 
Old 11-17-2007, 07:37 PM   #11
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Re: PPI side effects

Dear Flowergirl and Stardust,
Wow, I read your thread. I have posted on areas here but still looking for a solution to my problem. I have had chest pain, severe at times since Jan. I started PPI's plus antibiotics for H pylori. I have had this chest pain off and on for almost a year. Sometimes really bad, sometimes just a squeezing. Had a complete cardiac workup-normal, GB taken out ( had stones) and still chest pain..... this is so great I read this tonight. I was also diagnosed with low Parathryoid levels/ low vitamin D... and Dr's could not say why it happened. I think I will stop the PPI's and see if it goes away. How after you stop taking PPI's does the spasms stop?? I take calcium/magesium every day so I thought I was covering this area. Please let me know how you all are doing and maybe we can figure this out together. Thanks and God bless!!

 
Old 11-17-2007, 07:41 PM   #12
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Re: PPI side effects

Hi again!! I wanted to add to alternative remedies for PPI's. I read somewhere on this site that Pinenut oil and apple cider vinegar as a natural remedy. I personally have not tried it. Good luck and let us know if you do try it.

 
Old 11-18-2007, 12:55 PM   #13
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Re: PPI side effects

Hi tired,

The calcium and magnesium seems to have stopped the spasms, which is great. However, my nausea is worse again and so are the nightly episodes of drowning/choking (which is what I call them, but basically it's just the acid backing up, at least that's what I think.). That is my biggest problem right now. These choking episodes now seem to also happen during the day and are not restricted to nights anymore. I am thinking of calling my internist and scheduling an early appointment. I am supposed to be seeing him in a few weeks. I don't know if I can wait that long. Needless to say, I wish I didn't have to be dealing with this particular health issue. I am still wondering if any of my medications could be causing these highly unpleasant symptoms.
I took apple cider vinegar in the past. It is great for a number of things. I didn't have these problems then and took it for another reason. That's why I can't tell how well it works in reducing the acid reflux. I'll start taking it again - there's a bottle of organic ACV in the fridge right now. I haven't tried the pine nut oil but feel I should look into it. Good luck with your spasms!

flowergirl

 
Old 11-20-2007, 02:29 PM   #14
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Re: PPI side effects

Dear flowergirl2day,
I wanted to tell you I went to the Endocrinologist for check up , Calcium, magnesium, Parathryoid and vitamin D levels. The D and parathryoid were very low this August and I felt terrible. Took mega Vitamin D and felt better. I asked if PPI's could affect this and she said definitely YES!!( I think I asked GI dr. and they said NO). PPi"s affect absorption of these minerals.... wow, news to me. She suggested taking PPI early am and minerals in later afternoon and evening ( break up calcium or it is just excreted). She said 5-6 hours between PPI and minerals is good, not 1-2 as pharmacy suggests. Hope this helps someone out there.
As for me I felt better with chest pain and last night had reflux and "acidy feeling" stomach. I did not eat much at all, and very bland diet. How long til your "spasms" went away after stopping PPI. I have been on it for almost 11 months, Prilosec, Nexium, Protonix and now was taking Acidphex. I don't want to go back to gastritis, esophagitis so I am looking for some relief. They have told me all my chest pain is from esophageal spasms, cause unknown. Should I have cut PPI dose slowly,cut pill in half or taken every other day???? Any ideas from anyone. But the chest pain is there again today, not as severe but annoying and this is day 3 of no PPI. Shouldn't it be getting better??????
I go back to Gi Dr. end of Nov. Any ideas/info is greatly appreciated. god bless all and Happy Thanksgiving.

 
Old 11-20-2007, 10:02 PM   #15
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Re: PPI side effects

Tired,

thank you very much for your post. I will take your doctors' advice and take my calcium/magnesium/vitamin D supplement in the evenings from now on. I take my vitamins/supplements in the mornings with my medications. I did not know a 5-6 hour interval between the PPI and cal/mag supplement is recommended and really appreciate your sharing this. I have no doubt that the PPIs affect metabolism and absorption. And, possibly, a few other things as well. I have not stopped taking mine, though am beginning to wonder if I should. I will let my specialist make that decision. The cal/mag/vitD supplements took care of my cramps & muscle spasms. They happen when the drugs we take (or various health conditions) cause us to have electrolyte deficiencies.
I hope someone else out there has a few tips regarding quitting the PPIs.

Good luck to you!

 
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