Originally Posted by ladybud
Interesting that no TSH was done. Estrogen causes binding of the T4 to protein so it doesn't convert to T3. Functionally your labs look hypothyroid to me but I would treat with T3 (cytomel) only, since that is what appears deficient. Are you symptomatic? I don't believe in treating lab results if there are no symptoms to go with it (in general).
When I read the description of your family, my first thought was, do they have Cushing's? That is adrenocorticoid excess. Your cortisol level however was fine. The hypothyroidism can cause infertility when untreated. Low DHEA can cause low libido, so if that is a problem, it could be supplemented, but watch dose as it often causes acne!
High inflammation is usually a part of autoimmune diseases, so your thyroid issues could be Hashimoto's (need antithyroid antibodies checked for that) and your sis's liver problem could be autoimmune hepatitis. Just some thinking on paper for you to ponder.
Hello ladies - Welcome to my conundrum. :-)
Well we've all been tested for cushings, and we're all negative.
I've started seeing a doc who USED to be OBGYN and now does explicitly hormone and gyn. His story is a saw a need and decided to fill it when women kept coming back with ailments after having their kids and couldn't figure out what was wrong. Or their periods were all over the place like mine was, etc.
So he's diagnosed me with Stage 3 adrenal fatigue. He's taken me off of gluten, dairy, and soy (the soy only lasted like 5 minutes....it was ADDING stress trying to be so nitty gritty). He's also put me on DHEA, Pregnenalone, and Licorice Root sublingual drops. He had me do adrenal saliva tests to conclude a dosing for all of these. By way of results I don't really FEEL different, but I can SEE a difference around me. My house is cleaner on a more consistent basis, and I actually know what labido is!! That was exciting for a little while...
I also decided to follow up with a traditional endocrinologist. I just left his office and sobbed the whole way home. He essentially told me that there was nothing wrong with me and I just had bad genes, and there was nothing he could do to fix my genetics. He went through my labs and on one by one and said, "Well we don't recognized X and X anymore. TSH means nothing. And if you really had a T3 to T4 conversion problem you'd be a dwarf. That's what dwarfism is." Which was all code for, "You'll just be dumb, fat, and forgetful your whole life- Sucks to be you."