Re: can to much seizure meds cause a seizure?
I was on Kepp Zonegran Teg and Dilantin when I had problems. Thats the closest combo I can compare to in my ordeals.
My problems were weight loss due to Zonegran (so watch weight). That caused my Dilantin levels to increase above the acceptable range (10-20).
I FELL to the floor NOT in a seizure but due to balance/vision problems. I could "feel" there was a problem in my body, as odd as that sounds. The sensation that there were problems in my system when ramping up on Zonegran. This was only my second or third week of Z (so 200 mg/day, and when I just increased to 300).
As for too much meds causing problems, YES in some cases some drugs CAN if the levels are high in the persons body, thats the key part that has to be examined with blood work.
I'd check weight and see if any weight was lost when he was on Zonegran. That could be a reason why he is having problems with the other medications if a signifigant portion of body weight was lost. I lost nearly 20% of my body weight. in less than a month.
As for the Keppra side effects; atleast in MY case as an adult; I did not have increased seizures, but I had toxic symptoms of mild depression when I was on a high dose of 4000mg/day.
For TegXR on a high dose (3x day), the toxic "peak" effects last 1-2 hours after administering my meds, then would lessen; but after dropping back to my prior dose (2x day) there was no change in seizure frequency from the high dose to the previous dose of 1600mg/day. Only the side effects were thankfully gone.
Currently I am on 3000 of Kepp and 1200 of Teg XR with no problems of drug interactions. I think the Topa (450/day) MAY have a slight interaction with one of them, but the Topa levels have recently leveled out (well, a little high, but not low) and Teg has maintained where it had always came out at. Keppra varied slightly. I will hopefully hear back this week for the recent lab results that are in the clinic, but have yet to be reviewed.