Re: What is your experience with Topamax?
Topa the only major downsides I had were energy drain and appitite was effected.
After increasing from my initial dose after titrating up to 100mg BID, I bumped PM 100mg (so 100AM 200PM) and THATS where eating was effected. I had to adapt to forcing myself to eat. It made the mind think the body was not hungry. I could go two days without not eating and not feel hungry. Needless to say I learned quickly.
I went as high as 450/day on Topa before this spring I was lowered to 400. That small 50mg drop did amazing work on boosting the eating.
No real negatives on my side. Sleep can be effected if I get off cycle, but that could be Topa or Keppra. It takes me almost a week to get back on cycle when I get off track for sleep.
I have not been on monotherapy in ages. I have needed to be on three meds for the last about 10 years.
Keppra you have to be cautious on how fast they increase your dose. SOME patients can't take rapid increase (500mg bumps) and need to go with slower increases (250 or 125). Also don't think you need to be pushed to max dose as a lot of the Dr's try to (3000mg/day). If you start to feel "odd" or not normal, stop the increase and call the Dr. The MAIN side effect with Keppra reported is the emotional outbursts "KeppRage" as it has been called on the patient boards.
In MY case the dose the Dr put me on of Keppra (4000/day) caused a slow spiral case of mild depression where I felt unsafe alone. I called right away and he waved it off, saying it would go away. I stayed with it for over a month until it had worsened to where I didn't feel safe alone one night. I said I was going in to the Emergency Room. That solved my problems. They were shocked with my dose, shocked at my blood work, and told me to drop back to 3000. Problems went away within 24 hours.