I think things should be clarified, as this post doesnt seem to be completely accurate. Mononucleosis is a term that is often used to descibe a set of clinical symptoms and changes in the blood, one of which is an increased number of circulating monocytes from which the condition derives its name. This syndrome, which is usually chracterized by one or all of the symptoms of fatigue, fever, lymphadenopathy and sore throat was first associated with acute infection with the Epstein-Barr (HHV-4) virus, however it turns out that these symptoms and changes are often typical with numerous other acute viral infections. Acute cytomegalovirus(HHV-5) and HHV-6 (both viruses closely related to EBV) are very common infections and can cause syndromes which can be clinically indistinguishable from EBV associated 'mono' . Some doctors will refer to this as 'CMV or HHV-6 induced mononucleosis." So, again the term 'mono' can refer to the syndrome rather than the undelying viral cause.
When people say they have 'mono', they typically mean they have the symptoms of a primary EBV infection which can really only be confirmed through a blood test. Most confirmations are done through a test which looks for heterophile antibodies, although such antibodies might not always be present depending on the timing of the test, the person and the virus responsible for the condition. If one has the symptoms of mono, and their doctor comes back and tells them they are 'negative', they should ask specifically what test was administered to come to that conclusion and make sure that negative result is not just based on a heterophile monospot test. Causes of heterophile-negative mononucleosis include,as mentioned CMV, HHV-6, various hepatitis viruses etc. Someone with the symptoms of 'mono' with a negative heterophile test, and who wants to get to the bottom of their condition, should have viral antibody titer tests to EBV, CMV and HHV-6 performed, and perhaps to hepatitis viruses if there is liver dysfunciton. I wish my doctors, who insisted I had 'mono' knew this, as they failed to test me for HHV-6 which indeed was the cause of my mononucleosis, and which I didnt discover until months later and constant thoughts of 'what the hell is wrong with me?"
Originally Posted by _mystictiger_
Glandular Fever is caused by EBV AND Monoculeosis (MONO) and this is why it is called MONO. Your partners can become infected with it but chances are they already had Glandular Fever or EBV as a child and didn't have any symptoms. In this case they will not get GF.