deenie,
I wore glasses from age 10 to mid 50's, with 10 years off in the middle wearing "Stone-age" contacts (the hard, non-gas permeable kind).
My prescription was very similar to yours until my recent cataract surgery.
And I loved my glasses.
Don't just get any ol' kind of "high index" (light weight and thin). Get the most expensive, thinnest, lightest grade you can. It makes a big difference if you get the cheap or the middle-priced, so go for the high end.
The anti-reflective coating is a "must" too. When your lenses are thick, there are reflections you actually see on the lens from one side to the other when you're sitting by a lamp reading. The anti-reflective coating blocks this from happening. It also allows you to make direct eye contact with people when you're having a conversation. For my job that is/was a must-have.
The wider the lens, the thicker and heavier it will be on the outer edges, so don't go for the really wide rectangular frames they're starting to show now. I prefer rimless or metal frames because I don't like seeing the edge of a dark frame. When you're very nearsighted, you do notice those things. But my nearsighted boss just got heavy, dark frames and seems to like them. They would drive me batty.
I also have to have spring hinges and adjustable, non-slip nose pads, mostly because my ears are ridiculously sensitive to any pressure. My nose doesn't feel anything, so they can balance/grip it as firmly as necessary. You might be opposite with regards to ear/nose sensitivity. Either way, it's something to consider.
The spring hinges are nice for anyone, but even more so if you have a strong prescription and are going to put the glasses on before you get out of bed and not take them off again til you turn out the light. It allows you to put them on top of your head if you're sleeping in a train, or even fall asleep with them on and not tweak them out of shape. I prefer the spring hinges to the titanium frames with "memory" because my ears are at different heights and I don't want the frame to be "remembering" a perfectly symmetrical shape.
Obviously I could babble on more, but this should be enough for you to get started.
Happy frame shopping! It really is fun!