Re: What are all these medications your talking about?
I have used, variously, Neurontin, Ultracet, and Bextra, as well as a gazilliion other meds (most of which were useless). Never used Topamax.
Chris is correct: Ultracet is indeed Tramadol (brand name Ultram)diluted by acetaminophen. The dilution renders it basically non-narcotic,so you can take higher doses without worry about addiction. Ultracet is the *only* pain med that works *at all* for me so far (I had ulcers, so I can't take NSAIDS); Ultracet has *no* negative side effects for me, but its efficacy is relative to the severity of my pain.
Bextra is indeed an NSAID that is supposed to be easier on the stomach, but I can't even take 10mg/day without problems. Once in a great, great while (like once every few weeks), when the arthritis-y inflammation sensation gets beyond endurance, I'll take one, but I generallly have to cope without anti-inflammatories.
Neurontin was originally an anti-seizure medication prescribed for epileptics and those with other seizure disorders. Research then showed that it was effective for some sufferers of bipolar disorder (manic depression), so doctors began prescribing it on an "off-label use" basis for them. That evidence of effectiveness on brain chemistry apparently led to research on other brain neurotransmitters, and it was found to be effective on pain - particularly nerve pain - for some people. The first week or so that I took it (now about four years ago), it worked great, and thereafter quit working altogether. With very few exceptions, this has been my experience with most of the meds prescribed for FMS. I now take Paxil CR/ 25mg (which I take for depression anyway), Ultracet when I can afford it (no health insurance right now), and Adderall/10mg for fatigue and fibro fog. I also take guaifenesin (no results yet after a few months), probiotics for IBS, and just began chlorella for mercury chelation.