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Old 05-13-2005, 09:18 AM   #1
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Question Can Clonazepam make me depressed & tired?

My doc gave me clonazepam this week to help me sleep better. I am already on Flexiril and prozac but I just am so sick and tired of being sick and tired. I feel like I have no life anymore. I can't even make myself go to the pool and I love to swim and was doing 1/2 mile a few times a week up until about 2 weeks ago. I just can't make myself do much of anything! I bummed today. My hubby said it seems as if this new pill is making me worse. Could it be?

 
Old 05-13-2005, 10:11 AM   #2
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tkgoodspirit HB Usertkgoodspirit HB User
Re: Can Clonazepam make me depressed & tired?

Quote:
Originally Posted by mermaidx7
My doc gave me clonazepam this week to help me sleep better. I am already on Flexiril and prozac but I just am so sick and tired of being sick and tired. I feel like I have no life anymore. I can't even make myself go to the pool and I love to swim and was doing 1/2 mile a few times a week up until about 2 weeks ago. I just can't make myself do much of anything! I bummed today. My hubby said it seems as if this new pill is making me worse. Could it be?
Hi mermaid,

I used Klonopin/Clonazepam which is a benzodiazepine. It is an antsiezure medication and docs commonly prescribe this med for FM patients to help with Restless Leg Syndrome and to help them sleep. I was on it for 3 years and am now weaning off of the med and using Trazadone. Benzodiazepines are considered to be very addictive and you should not stop using them abruptly if you have been using them for an extended period. Like me, you have to "wean" off of them. Klonopin is at the top of the list for being the longest acting benzo type med. Meaning it stays in your system for 18 hours or more, therfore the longer you use this medication the more it builds up in your system and stays there. Usually a medication's "life" is based on how much you lose in your urine. That's why you may hear the term "this medication has a long "half-life", meaning it isn't lost through body waste and more than half of the medicine's compound stays in your system. For instance Lortab is a short acting med and only stays in your system for little more than 4 hours, if that. Okay, I have the information about the ADVERSE side effects you can experience from this medication listed. This list is usually given out to you when you first buy your meds. So incase you didn't keep your information paper, I have it here for you. Now remember these are considered ADVERSE side effects, and truthfully there are some words and terms there that I have no idea what they mean! But as with any med, you have to give it at least 2 weeks sometimes longer before you notice any benefits from it, or that the side effects aren't going to subside and maybe this med isn't for you. But you really need to allow it it's "breaking in" time. It's not fair to yourself if you don't give it time, unless of course you are having such awful side effects that make you feel you need to go to the emergency room, of course then you want to stop the med immediately.

Personally, for me, it worked wonders, and I don't recall any side effects. The reason I'm coming off of it after so long is at the recommendation of my Psyciatrist. The med can make you feel a little bit of a "hang over" effect in the morning, and plus, I have been on it for a long time.

You didn't mention what dosage you were on. It comes in doses as low as .125mg. Then it goes to .25mg, .5mg, 1mg and 2mg. I started on .5mg then after one year I bumped up to 1mg. 2mg of this med is considered a high dose. It may be that you are on too high of a dose. The only thing I would think that would be interfering with Clon. would be the Prozac. For some people meds like Prozac don't mix well with benzo meds. I used Flexeril and Klonopin together for awhile. Flexeril just didn't work for me. But Flexeril also has sedative tendencies as does Paxil. So you may have too many sedative type meds there. You are taking the Klonopin only at bedtime right? If not, that really should be the only time to take it. It's not meant for FM's to use throughout the day, usually prescribed once a day at bedtime. Oh and I keep using the word Klonopin because that is the brand name of Clonazepam and it's just easier to spell! If this med turns out not to be for you, I would suggest Trazadone. It is also given for sleep. It's usually given at a higher mg, but it isn't as sedatiting. Also, how is the Prozac working for you? I would like to mention a different med, Lexapro. It is also an anti-d but it also helps with anxiety. So for me, I use Lexapro and Trazadone as my anti-D and my sleep medication. I hate anti-D's used simply for Fibro, I have my own issues with them, but I have been dx'd with major depression so...Lexapro is good for me since I also have GAD (generalized anxiety disorder).

So, I've given you the list of side effects and some alternative meds you may want to check out incase you are still having problems. Please remember that this list is not meant to scare you. It comes right from the drug manufacturer and you know they have to list every possible side effect to satisfy the FDA, so don't be scared off by them. Like I said, there are words there that I have never heard of! And these are the EXTREME side effects. It is normal to experience some side effects when first using any new medication.

Bottom line, these medications are meant to change how our brain functions and "get it back on track", and since everyone's brain is unique, so are their reactions to many of these type meds. What works for me may not work for you, and vise versa. You will probably get many different answers to your question, but that's good, because it opens you up to more information and experience about this medication.

Good luck hun, and post back to let us know how it goes for you.
tk



Adverse Effects
The most frequently occurring adverse reactions to clonazepam are referable to CNS depression. Drowsiness occurs in approximately 50% of patients and ataxia in approximately 30%. In some cases, these may diminish with time. Behaviour problems have been noted in approximately 25% of patients and increased salivation in 7%.

Others, listed by system, are:

CNS: (Central Nervous System)
Alterations in behaviour, which have been variously reported as aggressiveness, argumentative behaviour, hyperactivity, agitation, depression, euphoria, irritability, forgetfulness and confusion. These behavioural reactions are particularly likely to occur in patients with a prior history of psychiatric disturbances and are known to occur in patients with chronic seizure disorders.

Other adverse reactions involving the CNS have included nystagmus, unsteady gait, slurred speech, dysarthria, vertigo, insomnia, and diplopia. Isolated reports of akinesia, hemiparesis, tremor, hypotonia, headache and choreiform movements have been received. Minor changes in EEG patterns specifically low-voltage fast activity.

Gastrointestinal:
Increased salivation, nausea, vomiting, anorexia, constipation, diarrhea, encopresis, dry mouth, increased appetite, abdominal pain, hepatomegaly.

Genitourinary: (I don't even know WHAT this IS!)
Rare instances of dysuria, nocturia, incontinence, urinary retention, enuresis.

Integumentary: (THIS either!)
Nonspecific erythematous, papular and maculopapular rashes, swelling of the face and eyelids, urticaria, pruritus. Hirsutism and hair loss have also been reported, but drug relationship has not been established.

Musculoskeletal: (Now THIS is familiar! )
Muscle weakness, low back pain.

Respiratory:
Hypersecretion in the upper respiratory passages, rhinorrhea, dyspnea, respiratory depression.

Hematopoietic: (I think this is referring to the blood)
Anemia, leukopenia (WBC below 4000/mm(3)), thrombocytopenia, eosinophilia.

Liver function:
Slight, transient elevations of transaminase and alkaline phosphatase.

Miscellaneous: (I know what this is too! LOL)
Palpitations, coated tongue, dehydration, fever, lymphadenopathy, weight gain or loss, changes in libido, gynecomastia, hallucinations, dysdiadochokinesis, coma, aphonia.

Last edited by tkgoodspirit; 05-13-2005 at 09:15 PM.

 
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Old 05-13-2005, 11:13 AM   #3
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lucylane HB User
Re: Can Clonazepam make me depressed & tired?

I'm so impressed by the reply given to depressed & tired. I found it very informative and I take clonazepam myself for pulsatile tinnitus. If you take it before bedtime, you have a great sleep, no bad dreams and you wake up refreshed and rested. Good Luck!

 
Old 05-13-2005, 11:30 AM   #4
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tkgoodspirit HB Usertkgoodspirit HB User
Re: Can Clonazepam make me depressed & tired?

Quote:
Originally Posted by lucylane
I'm so impressed by the reply given to depressed & tired. I found it very informative and I take clonazepam myself for pulsatile tinnitus. If you take it before bedtime, you have a great sleep, no bad dreams and you wake up refreshed and rested. Good Luck!

Hey lucy!

Thank you. Also, I forgot to mention what you just said about Klonopin not "knocking you out". I know a lot of medications given for sleep do that to some folks. I personally felt a wee bit of a "hung over" feeling when I first woke, but I have CFS and am always tired, so that is just my personal experience. The reason I am not using Klonopin anymore is simply because I was on it for 3 years.

Yes, it is very important to note that you DO experience dreams and you wake up during the night to "pee pee", but go right back to sleep. This is what Klonopin is meant to do for FM. You should not be put to sleep in a "vegetative" state! You should be dreaming and you should be waking if "the call of nature" hits you.

Thanks lucy, I had forgotten to mention that. I appreciate your chiming in!

tk

 
Old 05-13-2005, 04:54 PM   #5
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seaturtle HB User
Re: Can Clonazepam make me depressed & tired?

Hello,

This is just my experience with the Klonopin, doesn't mean it will be yours.
I couldn't take it, made me very depressed and tired, too. But I didn't stick with it, either.
For sleep, I use Ativan one mg, which works well most of the time. Have used it for three or four years now, minimal side effects, and without it, I don't sleep.
Sometimes I've found I have to begin with a mini-dosage, a child's dosage, and then work up slowly in order to tolerate meds.

I hope you find the med that is just the right one for you.

Blessings,

Seaturtel

 
Old 05-14-2005, 08:46 AM   #6
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lucylane HB User
Re: Can Clonazepam make me depressed & tired?

I'm on the minimum dose of clonazepam & effexor (anti-depression capsule). My doctor tells me I can double the dose on days I feel I need to. Since I'm on the min. dose probably explains why I wake up feeling rested and not dozy. I get up in the night to go to the washroom and fall right back to sleep quickly. I'm going to remain on these meds because it is so helpful in eliminating the heart beat noise I get in my right ear for most of the day (pulsatile tinnitus). Coffee even helps eliminate the noise. I drink 3 - 4 cups a day. I know it helps because before I was put on the meds, I noticed it gave me some relief.

It's true about clonazepam helping people with restless legs syndrome. I know this because my mom takes it and now she no longer has to suffer with that horrible ailment.

Last edited by lucylane; 05-14-2005 at 08:47 AM.

 
Old 05-31-2005, 04:58 AM   #7
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lucylane HB User
Re: Can Clonazepam make me depressed & tired?

I was given ativan when I went to the hospital, after having trouble taking deep breaths. That was a few years ago. When I was getting a prescription for an anti-anxiety med, I mentioned to the doctor the ativan and he said the hospital does use ativan as a quick fix to relieve anxiety (panic attacks), but he'd much rather prescribe me clonazepam. It does make you drowsy and can even bring you down. That is why, when I take it during the day, I make sure I take it with coffee to counteract the drowsiness effect and at bedtime without coffee, so I can sleep well. It's very important to take the proper dose of any medicine. I am lucky and can find relief using the minimum dose, so any side effects I may have are less. My mom takes 2 or 3 clonazepam at bedtime for restless legs syndrome and it helps her. I take 1/2 tablet of clonazepam at bedtime and it helps me. Like any drug, clonazepam is not for everyone, because we all react differently to the meds we take.

 
Old 01-07-2006, 02:56 PM   #8
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Rianna HB User
Re: Can Clonazepam make me depressed & tired?

I take Remeron as well as Klonopin (Clonazepam) 0.5 and have been taking it for about five months. It has helped a great deal with panic and anxiety that I have, and have not had any negative side effects. It helps with the depression instead of worsening it..it also helps with PMS symptoms as well (irritability, emotional, etc).

 
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