I just started Lyrica on Friday, 50 mg. 3x/day. The only side affect I've noticed is being a little tired, and kind of a mild drunk feeling. But honestly it's kind of nice because it has subdued my anxiety quite a bit. This is the first day where I feel it might be working, my pain is greatly reduced today. I have noticed I find myself eating more or craving more. But I'm hoping that with the pain reduction, I'll exercise more and counteract any weight gain.