I've had the injections in my ankles,knees,lower back, etc. I think it's the thought of hearing everyone talk about these shots that scare us so bad. But, DO NOT look at the needle. My OS is very good at giving these injections and he usually puts numbing meds with it. Just don't look and mostly you'll feel preasure. Anything hurts worse if you watch!
It may take a couple of days before it starts helping, but I have had many and only had maybe 2 or so that didn't help any.
They have really been life savers for me and at times it has only took 1 to get the job done.