Smallpox has been erradicated, so it is very unlikely that people could attack with it.
The only way anyone could possibly do that is by trying to break into one of the secure labs that store lethal viruses and bacteria where they work on them. These are Level 3 security and keep such diseases as Ebol virus, Anthrax, HIV, Hepatitis, E.Coli and others. These places are something like Porton Down, which is owned by the Ministry of Defence in England, but they are highly secure, so it is a very unlikely event.
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