Re: Which medication is a better pain reliever?
What you are talking about is Vicodin, well at least the brand name. You asked two questions. Which is a better pain reliever. Neither is better than the other, the vicodin with 625 acet. will increase your pain threshold more than the 325. As far as feeling one more than the other, I don't think the acet. inhibits the hydrocodone from working.
Regardless, there is a lot of acetaminophen in there. If you take more than the recommended dose you are at risk of major liver tissue death .. that stuff is toxic to your liver.