Iím female aged 60. My mother and grandmother both had underactive thyroid and I was told to look out for symptoms myself as there was a strong possibility that I would also develop this. I started get exhibiting symptoms like aches, coldness, terrible mental slowness and memory loss and pretty bad fluid retention. I also had weight gain. Pretty classic symptoms of hypothyroidism I thought. I went along to the doc who did the blood tests and said my TFT levels were out a bit and referred me to specialist who without even seeing me wrote back suggesting that I have some cardio checks because he thought I should not be exhibiting this level of symptoms. I guess he was thinking heart failure as an explanation of the fluid retention. Anyway I went along to cardio clinic and had ecg which showed ďa slight anomaly on the base lineĒ so this was followed up by a stress test and ultrasound scan. The results from the cardio clinic says the echocardiogram showed a non dilated LV with good LV systolic function. Is this good or bad? What does it mean? But the bit that really concerns me was that the myocardial perfusion scan showed mild inferior ischaemia and they want to proceed to angiogram. Well I looked ischaemia up and itís when a muscle is starved of oxygen, so ok I get that but what does inferior mean in this context? Could these symptoms have been caused by fear because I was terrified at the scan, could it have been caused by electrolyte imbalance because I have a bit of a problem with low potassium levels, could it even be caused by low thyroid levels which has now worsened. Does this really justify the risks associated with angiogram? I may be wrong but my feeling is that once you get into the cardio clinic its a bit like being on a conveyor belt and you are just run along the line and put through all the tests regardless. Probably should add that Iím on atanolol 100mg. Ramapril 10mg, doxazosin 2mg, simvastatin 40mg and frusimide 10mg. The atenolol and remapril is for a long standing high blood pressure problem and the doxazosin and simvastatin are recent additions prescribed by the cardio clinic. I think my blood pressure is a familial thing. both my parents had high blood pressure and i have had it from a very early age. It was first drawn to my attention when i was about 20. I also have a heart murmer which I've had from birth. Neither of these things has ever caused me any trouble. I have never had angina or chest pain. I'm avaragely active but no athlete. I'd really appreciate it if someone could explain the doc speak. Its very difficult to make decisions about things when you dont understand the facts and causes.