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Old 07-07-2003, 02:29 PM   #1
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Cool 99 Percent of Pegasys Responders Virus Free Up to Four Years Later

Howdy all-
In a response to some of the thoughts on treatment, this comes from one of the Doc pioneers on the Pegasys studys in Canada, I am on the Pegasys program as a "reward" for the results of this Doc and countless others, that put all their outstanding time and effort into the pegasys studys here In Canada,

This is a Quote from one of those leading Doc,s-

-99 Percent of Pegasys Responders Virus Free Up to Four Years Later


- Ninty nine percent of the hepatitis C patients who responded to treatment with Pegasys (peginterferon alfa-2a) have remained virus free up to four years later, according to results presented at the 38th Annual Meeting of the European Association for the Study of the Liver.[you can do a general search to find this]

"This information tells us that when a patient achieves a sustained virological response, they are indeed really 'cured',"Dr. Mark Swain, Associate Professor of Medicine at the University of Calgary in Canada "This is a critical message for patients whether they are about to start therapy or in the midst of it -- the end result is worth it."

Researchers for Roche, which markets the drug, said a possible explanation for the success of Pegasys may be found in another study showing that levels of the drug -- which hepatitis C patients take once weekly -- remain constant in the body over the seven-day period thereby suppressing the virus on a constant basis.

The researchers said that in contrast, half of patients treated with PEG-Intron (peginterferon alfa-2b) -- a rival drug marketed by Schering -- had no detectable drug in their bodies by the fifth day after their weekly injection, potentially resulting in renewed virus replication.

"Our study demonstrated a difference in drug levels between the two pegylated interferons," said Dr. Raffaele Bruno, University of Pavia, Italy. "We concluded that Peg-Intron should be intensified from its current once weekly dose to a twice-weekly dose to avoid the hepatitis C virus from replicating."

-Now I am sure Schering will respond to these comments, -a simple soultion, inject Peg-intron every five days instead of 7,

-For your info,


Someday we are going to make this right.
Oneday we are going to win this fight.

Neil


------------------
--Get Outdoors-Enjoy Life----Neil

[This message has been edited by LOST1 (edited 07-07-2003).]

 
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Old 07-07-2003, 03:56 PM   #2
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I hope and pray we are both in the top 99% of that class.

Now if we can just convince the drug manufacturers to lower their prices maybe everyone can be rid of this evil thing!

Jeannie

 
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Old 07-07-2003, 05:07 PM   #3
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Awwww, that doesn't sound very good for me . . . <sigh>.

 
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Old 07-07-2003, 10:55 PM   #4
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Doone

Don't fret, the success rate for PegIntron is not far behind Pegasys. The positive attitude makes up a lot for the success, so keep your chin up.

Diana

 
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Old 07-08-2003, 12:45 AM   #5
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I hear ya Lorna <sigh>
Maybe I am reading too much info lately, I think I need to take a break and stay focused for hubby and not lose sight that he will beat this as a geno 1b.

Hang in there and we need to stay positive as diana says!

faith *hugs*

 
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