It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



High Cholesterol Message Board
Post New Thread   Closed Thread
LinkBack Thread Tools
Old 04-02-2006, 01:26 PM   #1
Senior Veteran
(male)
 
Join Date: May 2004
Posts: 1,069
NHone HB User
Cerebellar Ataxia and cholesterol lowering medication

Has anyone been told they have Cerebellar Ataxia of "Symptoms consistent with Cerebellar Ataxia" while they were taking cholesterol lowering medications of any kind?

 
Old 04-08-2006, 02:35 PM   #2
Junior Member
(female)
 
Join Date: Apr 2006
Posts: 16
uneamie HB User
Re: Cerebellar Ataxia and cholesterol lowering medication

Quote:
Originally Posted by finres
Has anyone been told they have Cerebellar Ataxia of "Symptoms consistent with Cerebellar Ataxia" while they were taking cholesterol lowering medications of any kind?

My mother passed away 5 years ago from "Cerebellar Ataxia". She never took statins, however my doctor just perscribed "Pro****l" 40 mg's for me. I bought them...very costly but they are stitting in my med's cabinets unopened. I am very frightened to take them and knowing my mother's history of Ataxia and not knowing if it was genetic or caused by a viral infection, I am refusing to take them at this time. I do not want to open the door to this monster of a disease. My mother suffered a very slow and painful death. Just the idea that statins can interfer with one's muscular system is enough to scare the heck out of me.

I am working on lowering my cholesterol naturally by weight reduction, red yeast rice tablets, red wine and fish oil tablets. If after 6 months of time I cannot lower it with this method I will rethink the statins....but it's going to take a lot convince me.

 
Sponsors Lightbulb
   
Old 04-08-2006, 09:16 PM   #3
Senior Veteran
(male)
 
Join Date: May 2004
Posts: 1,069
NHone HB User
Re: Cerebellar Ataxia and cholesterol lowering medication

Quote:
Originally Posted by uneamie
My mother passed away 5 years ago from "Cerebellar Ataxia". She never took statins, however my doctor just perscribed "Pro****l" 40 mg's for me. I bought them...very costly but they are stitting in my med's cabinets unopened. I am very frightened to take them and knowing my mother's history of Ataxia and not knowing if it was genetic or caused by a viral infection, I am refusing to take them at this time. I do not want to open the door to this monster of a disease. My mother suffered a very slow and painful death. Just the idea that statins can interfer with one's muscular system is enough to scare the heck out of me.

I am working on lowering my cholesterol naturally by weight reduction, red yeast rice tablets, red wine and fish oil tablets. If after 6 months of time I cannot lower it with this method I will rethink the statins....but it's going to take a lot convince me.

I know how devastating that cerebellar ataxia can be. People don't seem to realize that you might be under a cloud the rest of your life not knowing if she had the genetic kind. A specialist in California recently said that my mother most likely has "cerebellar ataxia syndrome" caused by lipid lowering therapies. (zocor, lipitor, zetia). However, hers started with imipramine (she was given this for urinary incontinence-which was caused by her doctor prescribing calcium channel blockers, and too much calcium). 12 other compounds are know to cause this also. amiodarone, amitriptyline, chlorcyclizine, chlorpromazine, clomipramine, fluoxetine, imipreamine, perhexiline, tamoxifen, thioridazine, and zimelidine. The bind to the NPC 1 protein and while cholesterol synthesis is normal, it hides cholesterol in pockets in the body, (brain, liver, other organs). Yes is lowers the serum cholesterol in the body...the only kind of cholesterol that doctors check. In recent months it has been shown that Zetia works on the NCP1 L1 pathway.. You can look up niemann pick and symptoms....guess what ataxia. I don't know if your mother had atrophy of the cerebellum....or if she had the spino cerebellar genetics test. After a lot of research, (and stupid answers from doctors) I was assured by an ataxia specialist that cerebellar ataxia is not genetic...only SPINO-cerebellar ataxia. I would not take the cholesterol medication, if my cholesterol was 3000!!!! Also the only kind of cholesterol that is dangerous is oxidized cholesterol. Hope this helps...I have a conference call with a niemann pick specialist to see if Zetia can lower serum cholesterol, but hide it away in truly dangerous areas. (so far a bio-chemist says yes....if it works on the pathway that they now say it does) (it was merck (the maker of zetia) that just now found the pathway. Nothing like not knowing how your drug works, but that it just lowers cholesterol!!!!!!

 
Old 04-09-2006, 08:24 PM   #4
Junior Member
(female)
 
Join Date: Apr 2006
Posts: 16
uneamie HB User
Re: Cerebellar Ataxia and cholesterol lowering medication

Quote:
Originally Posted by finres
I know how devastating that cerebellar ataxia can be. People don't seem to realize that you might be under a cloud the rest of your life not knowing if she had the genetic kind. A specialist in California recently said that my mother most likely has "cerebellar ataxia syndrome" caused by lipid lowering therapies. (zocor, lipitor, zetia). However, hers started with imipramine (she was given this for urinary incontinence-which was caused by her doctor prescribing calcium channel blockers, and too much calcium). 12 other compounds are know to cause this also. amiodarone, amitriptyline, chlorcyclizine, chlorpromazine, clomipramine, fluoxetine, imipreamine, perhexiline, tamoxifen, thioridazine, and zimelidine. The bind to the NPC 1 protein and while cholesterol synthesis is normal, it hides cholesterol in pockets in the body, (brain, liver, other organs). Yes is lowers the serum cholesterol in the body...the only kind of cholesterol that doctors check. In recent months it has been shown that Zetia works on the NCP1 L1 pathway.. You can look up niemann pick and symptoms....guess what ataxia. I don't know if your mother had atrophy of the cerebellum....or if she had the spino cerebellar genetics test. After a lot of research, (and stupid answers from doctors) I was assured by an ataxia specialist that cerebellar ataxia is not genetic...only SPINO-cerebellar ataxia. I would not take the cholesterol medication, if my cholesterol was 3000!!!! Also the only kind of cholesterol that is dangerous is oxidized cholesterol. Hope this helps...I have a conference call with a niemann pick specialist to see if Zetia can lower serum cholesterol, but hide it away in truly dangerous areas. (so far a bio-chemist says yes....if it works on the pathway that they now say it does) (it was merck (the maker of zetia) that just now found the pathway. Nothing like not knowing how your drug works, but that it just lowers cholesterol!!!!!!

Wow...you've really done some research there. Actually I did a bit myself but just today found an article that mentioned something about "statins depleating the body of the enzyme CoQ10 which can then cause "myopathy" and they suspect "cellebellar ataxia" among other things. This enzyme is especially needed for the heart which is a muscle. They are doing extensive research and believe that supplements of this enzyme can help Ataxia, Parkinsons and MS patients etc.

I believe my mother had atrophy-deterioration of the brain stem but she was tested several times for the genetic strain as well. The doctor believed that her ataxia was not genetic but he never finished a complete genetic work up before she died. In order to rule out that it was genetic he had to test her for every single strain of ataxia which he claims are many. He believed she ended up with it due to a virus or a brain injury. She had about 15 shock treatments at one time in her life so it may be possible that it injured her brain and showed up when she got older. We don't know for sure. I just feel that the doctors were sooo vague on giving information about Ataxia and it's causes.

Having watched her slow death and the misery she went through I am just very skeptical about taking any medications. At the moment I am on high blood pressure and "metformin" for diabetes. I think that is about enough for me. Do not want any more pills in my body.

I am doing the "red yeast rice" and taking supplements of CoQ10...hopfully this will work.

Thank you for posting all that information. It was enlightening. I will have to look further into it.

 
Old 04-09-2006, 09:46 PM   #5
Senior Veteran
(male)
 
Join Date: May 2004
Posts: 1,069
NHone HB User
Re: Cerebellar Ataxia and cholesterol lowering medication

any time....from what i understand about ataxia....its highly likely that the shock treatments caused the damage to the cerebellum. beta blockers (high blood pressure) also deplete Coq10. As they told us, most likely if no family member had cerebellar ataxia it is highly unlikely that it is genetic. I can't remember how many genetic types of ataxia there are, but I believe that it is about 15. Mother had all of the genetic panels done at Athena through Washington university in st. louis. THey are very vague on ataxia....because ataxia in itself just means movement disorder...thats all. Kind of if you don't know whats wrong put it there. If it was of the brain stem that would be different than cerebellar ataxia. If she was depressed, there is a good chance that she took one of the drugs i mentioned. If so in that instance she probably has a lipid disorder...(look up niemann pick) Niemann pick is genetic, but these medications create a psuedo niemann pick....(which mimics np but is not the actual disease). Also Zetia works on this same pathway, which is something that they just made public...(i bet they knew all along). What blood pressure medication are you on? Some can raise triglycerides, expecially the beta blockers, except Coreg. Also some can raise cholesterol. I'm glad that someone understands the reason why i usually blast statins. You know what cerebellar ataxia is like. Since doctors under report statin side effects, we never know how many people are affected and how they are affected. You Coq10 is probably the best thing you could do. Dr DiMauro, and ataxia expert at cornell...has confirmed in published papers that they believe the Low Coq10 in the cerebellum was problably the initiating cause that caused the brain damage that lead to cerebellar ataxia. You probably need to take 600mg of Coq10 to be on the safe side. Dr. DiMauro suggest the 600 when you have suspected mitochondrial damage. ALso you're right about the parkinson's. Many people say it doesn't help them. However it has been proven that it can stop the progression of parkinson's, and about a lot of people have noticed a reduction of 44% in their symptoms. You also might be interested to know that Merck (zocor) has held a patent since 1990 for Zocor plus Coq10... (however they don't make it)...look it up, its interesting to note the reason for adding the Coq10. It will be the smoking gun (with finger prints) when the law suits over statins start to hit the courts.

 
Old 04-10-2006, 11:05 AM   #6
Junior Member
(female)
 
Join Date: Apr 2006
Posts: 16
uneamie HB User
Re: Cerebellar Ataxia and cholesterol lowering medication

Quote:
Originally Posted by finres
any time....from what i understand about ataxia....its highly likely that the shock treatments caused the damage to the cerebellum. beta blockers (high blood pressure) also deplete Coq10.

If she was depressed, there is a good chance that she took one of the drugs i mentioned.

What blood pressure medication are you on? Some can raise triglycerides, expecially the beta blockers, except Coreg. Also some can raise cholesterol.
I have always suspected the "shock treatments" more so than any medications since my mother always refused to take them. She was very stubborn in that way. But, then again she was in a mental institution for 6 months so who knows what kind of medication they had her on while in there. She originally had a severe mental breakdown and detachment from reality and needed the shock treatments to bring her back so to speak. While the treatment did work and allowed her to live a somewhat normal life for at least 20 years prior to the "ataxia", I fear in the long run it just exchanged one problem for another.

As for the "blood pressure" meds that I am currantly on it is called; Felodipine extended release. I am going to do some research on this and see what I come up with for the coralation to high cholesterol etc.

It is amazing to me how little most "general family doctors" know about the medicines they are perscribing. I actually had to remind my doctor that I had a high liver enzyme count and that I needed to wait to get it down before taking the statin he perscribed.....that's scary to me and yet another reason why I do not want to take this. My liver count goes up if I take so much as an asprine.

Well...I am off to do more research...thank God for the Internet! Thanks again!

Last edited by uneamie; 04-10-2006 at 11:06 AM.

 
Old 04-10-2006, 09:39 PM   #7
Senior Veteran
(male)
 
Join Date: May 2004
Posts: 1,069
NHone HB User
Re: Cerebellar Ataxia and cholesterol lowering medication

I didn't find much on your felodipine (plendil)....I would not increase the effects of statins as some calcium channel blockers do. The ataxia scares me to death. I don't think people on statins realize that sometimes, minor muscle aches and pains can signal the start to something as severe as cerebellar ataxia. The older a person gets the less likely they are to recover. i do think you have enough evidence to say your mothers was not genetic. ALso look up LOW cholesterol and mental illness. I believe sometimes that the cholesterol is there helping us (i know). Again you can point out to your dodctor, that all statin makers say DO NOT take statins with abnormal liver panels...... (in our case , i would never take them)

 
Old 04-11-2006, 08:08 AM   #8
Junior Member
(female)
 
Join Date: Apr 2006
Posts: 16
uneamie HB User
Re: Cerebellar Ataxia and cholesterol lowering medication

Quote:
Originally Posted by finres
I Again you can point out to your dodctor, that all statin makers say DO NOT take statins with abnormal liver panels...... (in our case , i would never take them)
I agree. I think he feels that since my levels went down that it's OK to take them now but I say, on the contrary, my levels go up and down all the time so that is an indication that my liver is sensitive to toxins etc and should not be exposed needlessly.

What my doctor and many others do not get is that I would rather die in my sleep of a heart attack, or face the repercussions of a stroke, then to EVER experiece the hell of ATAXIA. My mother was the victum of ignorance on many doctors parts and I don't necessarily blame them for they are not GOD. But I do feel we have to look out for ourself and make sure that we are not being sold a bill of goods that will kill us in the end.

 
Old 04-11-2006, 08:41 AM   #9
Senior Veteran
(male)
 
Join Date: May 2004
Posts: 1,069
NHone HB User
Re: Cerebellar Ataxia and cholesterol lowering medication

I agree 100%....Until people have seen cerebellar ataxia, they have no idea what it is.

 
Closed Thread

Similar Threads
Thread Thread Starter Board Replies Last Post
Cerebellar Ataxia kkjha1959 Open to All Other Health Topics 1 03-26-2008 07:11 PM
Anyone successfully lower cholesterol by diet and exercise? Love2Read High Cholesterol 40 08-25-2007 03:19 AM
Cerebellar ataxia due to pneumonia kcferret Brain & Nervous System Disorders 1 07-20-2007 04:45 AM
High Cholesterol - Zocor roachbug High Cholesterol 39 05-12-2007 11:08 PM
Cerebellar Anaemia and Congenital Hypoplastic Anaemia GianroccoG Open to All Other Health Topics 0 11-28-2006 06:21 AM




Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is Off
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off




Join Our Newsletter

Stay healthy through tips curated by our health experts.

Whoops,

There was a problem adding your email Try again

Thank You

Your email has been added




Top 10 Drugs Discussed on this Board.
(Go to DrugTalk.com for complete list)
Aspirin
Crestor
Lipitor
Niaspan
Pravachol
  Simvastatin Tricor
Vytorin
Zetia
Zocor




TOP THANKED CONTRIBUTORS



JJ (25), yackedar (24), jenj770 (13), ARIZONA73 (10), rudiraven (10), Titchou (5), phil58 (4), AussieBloke (4), ladybud (4), Lenin (3)

Site Wide Totals

teteri66 (1180), MSJayhawk (1013), Apollo123 (909), Titchou (856), janewhite1 (823), Gabriel (763), ladybud (755), midwest1 (671), sammy64 (668), BlueSkies14 (607)



All times are GMT -7. The time now is 07:36 PM.



Site owned and operated by HealthBoards.comô
Terms of Use © 1998-2014 HealthBoards.comô All rights reserved.
Do not copy or redistribute in any form!