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Old 05-04-2006, 12:15 PM   #1
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Medications that can lower Coq10

Medications that can lower the levels of Coq10 in the body include statins for cholesterol (atorvastatin, cerivastatin, lovastatin, pravastatin, simvastatin), fibric acid derivatives for cholesterol (specifically, genfibrozil), beta blockers for high blood pressure (such as atenolol, labetolol, meoprolol, and propranolol, coreg) and tricyclic antidepressants medications (including amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine), and some anti-diuretics including HCTZ.... I have another more complete list from the NIH (national institute of Health) but have to look for it.... The cerebellum (part of the brain) is very sensitive to a number of drugs, and is especially sensitive to the lowering of Coq10.

 
Old 05-05-2006, 05:31 PM   #2
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Re: Medications that can lower Coq10

finres, do you know if cloniidine or verapamil lowers coq10. Are there any supplements that lower coq10? thanx for any info you may be able to provide.

 
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Old 05-06-2006, 03:25 PM   #3
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Re: Medications that can lower Coq10

Quote:
Originally Posted by lane413
finres, do you know if cloniidine or verapamil lowers coq10. Are there any supplements that lower coq10? thanx for any info you may be able to provide.
Clonidine is on the NIH list. Verapamil is not. you can find the list search (NIH medications that lower CoQ10). I havn't found any supplements that lower Coq10 except there is a potential for policosinol (red yeast rice). Also a doctor in texas (well know) did blood test with a new blood diagnostic tool (machine) that he has. He aslo found that Zetia lowered Coq10. He was not sure if it stops the production of Coq10 or stops the absorption. He was taking Coq10 supplements at the same time, and had prior to starting the test. This would be in contradiction to what the makers of Coq10 say...but hey, they didn't even know who Zetia worked when that first got it approved....That in itself is pretty scarey..(good old FDA). This fact is not a secret, as it is readily available informatioon.

 
Old 05-06-2006, 04:45 PM   #4
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Re: Medications that can lower Coq10

Quote:
Originally Posted by finres
Clonidine is on the NIH list. Verapamil is not. you can find the list search (NIH medications that lower CoQ10). I havn't found any supplements that lower Coq10 except there is a potential for policosinol (red yeast rice). Also a doctor in texas (well know) did blood test with a new blood diagnostic tool (machine) that he has. He aslo found that Zetia lowered Coq10. He was not sure if it stops the production of Coq10 or stops the absorption. He was taking Coq10 supplements at the same time, and had prior to starting the test. This would be in contradiction to what the makers of Coq10 say...but hey, they didn't even know who Zetia worked when that first got it approved....That in itself is pretty scarey..(good old FDA). This fact is not a secret, as it is readily available informatioon.
Finres...I tried a web search with the words U mentioned, but can't seem to find any list. Do U happen to have the url for it? I was wondering about Avapro or Atacand. I mentioned to my dr. about having some backaches with the Avapro and she gave me samples of Atacand, and also ordered a back X-ray, which I had done friday. I looked up that Atacand, and the side effects look worse then the Avapro, plus I read it is fairly expensive, even more then the Avapro, and that has gone up alot the last few months. I swear this dr. thinks I am made of money...NOT!!! U know she also gave me samples of Zetia, which are now in the trash, as I am NOT about to go thru what I did with all the other cholesterol lowering things I have tried.
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Old 05-07-2006, 02:17 PM   #5
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Re: Medications that can lower Coq10

Quote:
Originally Posted by JJ
Finres...I tried a web search with the words U mentioned, but can't seem to find any list. Do U happen to have the url for it? I was wondering about Avapro or Atacand. I mentioned to my dr. about having some backaches with the Avapro and she gave me samples of Atacand, and also ordered a back X-ray, which I had done friday. I looked up that Atacand, and the side effects look worse then the Avapro, plus I read it is fairly expensive, even more then the Avapro, and that has gone up alot the last few months. I swear this dr. thinks I am made of money...NOT!!! U know she also gave me samples of Zetia, which are now in the trash, as I am NOT about to go thru what I did with all the other cholesterol lowering things I have tried.
JJ. Sorry about that, search (NIH drugs that deplete CoQ10) i did this on yahoo or google, it was the first thing on the list. Avapro says use with extreme caution with potassium sparing diuretics, also avoid with cornary disease, also elevations in liver enzymes occur frequently. Atacand says back pain can occur in about 3%. I suppose you take this for blood pressure? Perhaps another type of blood pressure medication. Mother has done very , very well on coreg. unlike other beta blockers, it does not raise blood sugar. She also takes diovan, although a very small amount.

 
Old 05-07-2006, 04:43 PM   #6
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Re: Medications that can lower Coq10

Thanx Finres. I bet my mom's dr. would dispute this info, everytime I take her to the dr. with new info, he gets mad. He asked where did you get your license. I am so sick this, my mom is very sensitive to most drugs. She has gone thru just about every class with bad side effects.

I am afraid my mom will end up ill like your mom bcuz sometimes she gives up and follow these stupid doctors. She has diabetes and thyroid problems and she sometimes give up. While I am at work my dad watches her and make sure she only takes the meds I leave out for her. My mom used to fight with the doctors, but I think she just gives up sometimes. Thanks again!

p.s. how is your mom doing now? Is she taking any cholesterol meds?

 
Old 05-07-2006, 05:26 PM   #7
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Re: Medications that can lower Coq10

Quote:
Originally Posted by finres
JJ. Sorry about that, search (NIH drugs that deplete CoQ10) i did this on yahoo or google, it was the first thing on the list. Avapro says use with extreme caution with potassium sparing diuretics, also avoid with cornary disease, also elevations in liver enzymes occur frequently. Atacand says back pain can occur in about 3%. I suppose you take this for blood pressure? Perhaps another type of blood pressure medication. Mother has done very , very well on coreg. unlike other beta blockers, it does not raise blood sugar. She also takes diovan, although a very small amount.
Thanx finres, I came across that the other day but paid it no mind, think I had BRAIN FOG that day! LOL Some days I worry about myself, trust me.

So far all my bloodwork has come back fine, no problems, in fact I had low potassium levels, that is why they shoved me on the Avapro. From what I see, just about all the ARB's give U backaches, and even if they listed it as 1%, tust me, I would be the one to get it. I'm so stinking sensative to meds. it is pathedic.......

I also looked up my insurance, and the Atacand is not only more expensive, they don't list it as being covered, so will have to call monday and ask. Like hubby said, in a few months I will be on Medicare, imagine that at the ripe old age of "39"!!! LOL Now we will have to see if they would cover it. Good grief, like I said, this dr. must think I have a money tree in my yard!! She isn't the easiest person to talk with either.

Glad your mom is doing well on her new meds., it is a pain when U are sensative to things. Have a good one, and Thanx again......
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Old 05-07-2006, 05:33 PM   #8
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Re: Medications that can lower Coq10

Quote:
Originally Posted by lane413
Thanx Finres. I bet my mom's dr. would dispute this info, everytime I take her to the dr. with new info, he gets mad. He asked where did you get your license. I am so sick this, my mom is very sensitive to most drugs. She has gone thru just about every class with bad side effects.

I am afraid my mom will end up ill like your mom bcuz sometimes she gives up and follow these stupid doctors. She has diabetes and thyroid problems and she sometimes give up. While I am at work my dad watches her and make sure she only takes the meds I leave out for her. My mom used to fight with the doctors, but I think she just gives up sometimes. Thanks again!

p.s. how is your mom doing now? Is she taking any cholesterol meds?
Gosh your mom sounds just like me, sensative to everything. Don't ya just love these drs. that get annoyed when U have info. they didn't provide? Mine is the same way, and I get nasty looks. Oh well, too bad, either she calms down, or she will be on my list of DRS. FIRED next!!! Tell your mom not to give up fighting, as like my old dr. used to tell me, only I know how I feel, he can only go by what I tell him. Some of these new ones have an attitude, but if they get too high and mighty with me, I drop em. I don't care if I go thru every dr. in CT. till I find one that will listen to me and at least work with me, I will not give into their sarcastic remarks, or their fear tactics!!

Take care, and hope your mom does better and the dr. listens.......
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Old 05-07-2006, 09:07 PM   #9
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Re: Medications that can lower Coq10

Quote:
Originally Posted by lane413
Thanx Finres. I bet my mom's dr. would dispute this info, everytime I take her to the dr. with new info, he gets mad. He asked where did you get your license. I am so sick this, my mom is very sensitive to most drugs. She has gone thru just about every class with bad side effects.

I am afraid my mom will end up ill like your mom bcuz sometimes she gives up and follow these stupid doctors. She has diabetes and thyroid problems and she sometimes give up. While I am at work my dad watches her and make sure she only takes the meds I leave out for her. My mom used to fight with the doctors, but I think she just gives up sometimes. Thanks again!

p.s. how is your mom doing now? Is she taking any cholesterol meds?
Mother recovered from by-pass surgery very , very well. They almost killed her again by giving her cordarone. I found on the FDA medwatch that cordarone should be a drug of LAST resort. It also says the per the FDA ALL patients receiving it MUST be given and informational brochure on the medication stating the risks. (she never was) They gave it to her first and as a precaution...very against FDA warnings. Also the FDA lists that 50% of the people that take it get phospholipidosis (this is when cholesterol builds up with in the cells and can't get out). Her HDL went from 42 to 22, a sure sign of phospholipidosis. Your cholesterol can be very low with phospholipidosis. You will also get a fatty liver. Cholesterol lowering medications will not help this matter...in fact cordarone binds to the Niemann Pick protein NPC1...Zetia binds to the Niemann Pick protein NPC1L1. They really messed up both of the Niemann Pick proteins. Lexi-comp states also that zetia and all cholesterol medications should be suspended several days before elective surgery. They started her on Zetia before the surgery. We hope that a specialist in CA can help her with the cerebellar ataxia syndrome caused by lipid lowering thearpy. He is really the only doctor skilled in the US on lipid lowering (cholesterol) thearpy damage. He said we must have a muscle biopsy because liver tests have been shown to not detect a majority of the damage, and the damage can also affect the heart. Mother did well after her surgery because of her taking CoQ10 and magnesium, which see started in late 2003, when her problems began to surface. I will let you know what the specialist finds out, and how he is treating her.. Again thanks for asking about mother,...i appreciate it. (we have to get her off of the zetia...but her doctors keep saying her arteries will immediately clog up) yeah right... the mitochondrial damage is what caused her problems.

 
Old 05-08-2006, 11:31 AM   #10
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Re: Medications that can lower Coq10

Finres...Talked to my pharmacist about the Atacand, he told me it is about the same as the Avapro, so if I am having problems, he doubts it will go away by switching, and yes, it is a lil more expensive. I'm sure the dr. will have a hissy fit when I tell her, but oh well, TUFF! Noone has called me about the back X-rays, so I will wait till they call, then tell her about the meds., that ought to make her day. If she can't come up with a different med. to help, then forget it, as at least my bloodwork is ok with the Avapro, I'll just add Tylenol when needed. Going to wait a week before I even mention the Zetia she gave me, as that will probably send her over the edge for sure.

Hope all is well, and TTYL.......
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Old 05-08-2006, 07:13 PM   #11
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Re: Medications that can lower Coq10

JJ my mom took avapro and she suffered the bach pain also. She had told her new dr. that it caused her problems several yrs ago, but he insisted she try it again. She did and the same thing happened. Then on Easter weekend, she became severely allergic and had to go to the ER.

Why don't doctors just listen to the patient? She's not having problems with the zocor, but it can't be taken with verapamil.

 
Old 05-08-2006, 09:14 PM   #12
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Re: Medications that can lower Coq10

Quote:
Originally Posted by lane413
JJ my mom took avapro and she suffered the bach pain also. She had told her new dr. that it caused her problems several yrs ago, but he insisted she try it again. She did and the same thing happened. Then on Easter weekend, she became severely allergic and had to go to the ER.

Why don't doctors just listen to the patient? She's not having problems with the zocor, but it can't be taken with verapamil.
Oh lane, some of these drs. I think get upset when U confront them with any lil bit of knowledge U might have. Maybe they feel like your trying to outdo them or something, I haven't a clue. I'm not trying to show her up or anything, I just want her to work with me to get to the root of a problem. Oh well, sooner or later, hopefully sooner, it will get resolved without a big hassle.

Sorry your mom got so sick, that must have been horrid, especially on a holiday weekend. Sheesh, what kind of a nasty reaction did she have to cause her to go to the ER? Is she on both the Vermapril and Zocor, and how does she take them if they are not compatible? Good Lordy, isn't life complicated enough without having to hassle with drs.? A friend of our's had a very nasty reaction to Lispiril (sp.?), guess after a few months on it got nasty welts on his face. Now they have him on Norvasac, and he said he feels horrid, but the dr. told him to stay on it for a few more weeks to see how it goes. This guy is no baby either, and when he says he feels crummy, he does, and to be honest, he doesn't look so swift either. Oh well, hopefully either he will do better on it, or the dr. will change his meds.

Glad your mom is doing better, and hope it stays that way....
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Old 05-11-2006, 04:18 PM   #13
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Re: Medications that can lower Coq10

JJ, I hope you and your dr. can resolve the issue. I agree with you that the patient and the dr. should work together. A dr. shouldn't insist on having his/her way with somebody else's body.

My mom took lisinopril for over five yrs with great results. Then she had an allergic reaction and was taken off lisinopril. She tried the avapro and got the same reaction. Norvasc was a really bad med for her, but toprol xl was the all time worst. No she stopped the zocor until she sees the dr. tomorrow. He's going to be angry bcuz she saw another dr. in his office and was told NOT to take verapamil and zocor together.

What bp med are you taking now? I've read many of your posts and it seems you're like my mom, very sensitive to meds.

 
Old 05-11-2006, 06:13 PM   #14
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Re: Medications that can lower Coq10

Quote:
Originally Posted by lane413
JJ, I hope you and your dr. can resolve the issue. I agree with you that the patient and the dr. should work together. A dr. shouldn't insist on having his/her way with somebody else's body.

My mom took lisinopril for over five yrs with great results. Then she had an allergic reaction and was taken off lisinopril. She tried the avapro and got the same reaction. Norvasc was a really bad med for her, but toprol xl was the all time worst. No she stopped the zocor until she sees the dr. tomorrow. He's going to be angry bcuz she saw another dr. in his office and was told NOT to take verapamil and zocor together.

What bp med are you taking now? I've read many of your posts and it seems you're like my mom, very sensitive to meds.
Hi lane..Sorry to hear your mom has had so many problems, but as U said, I seem to be the same way...VERY sensative to meds. A friend of mine had a nasty reaction to Lisinopril also, he is now on Norsac, but still feels crummy, but his dr. told him to stay on it and will see him in a month. I hear so many folks crab about their drs. not listening to them, guess it must be the modern way or something.

The Avapro seemed to be doing well for me for the last year, but like I said, the last few months I have had nasty backaches. She gave me samples of Atacand to try, so I took one today, we will see if it is any good. I tried Diovan and got wicked backaches from day 3, and Altace drove me insane with the cough. If the Atacand doesn't work, I'll just go back to the Avapro till I ever find something that agrees with me. I talked with the pharmacist, and he told me that if I get backaches with Diovan and Avapro, it is highly likely I will with the Atacand as well, but hey, I'm trying it.

Still haven't heard a word about my back X-ray, and the gal that did it said the dr. should have results by monday. My drs. office has notices all over the office..DO NOT call for test results, U will be notified by mail or phone when results are availeable. Sheesh, to me that is like saying they don't want U to bother them. I'm calling tomorrow whether they like it or not, and if they get snippy with me, tuff, I can be snippy too.......

Best to your mom and hopefully she gets some decent news, and maybe we should start getting mad at these drs. and see how they like OUR attitudes.

Keep me posted, and I will U as well......
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