It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....

High Cholesterol Message Board

Crestor v Zocor potency?

Post New Thread   Closed Thread
LinkBack Thread Tools Search this Thread
Old 01-02-2007, 01:46 PM   #1
Senior Member
Join Date: Sep 2006
Location: USA
Posts: 292
jkhh HB User
Crestor v Zocor potency?

Does anyone have an opinion as to which they would consider more potent (in terms of side-effects, danger, etc), Crestor 5 mg or Zocor 20 mg? I am taking Vytorin 10/20 but I thought it would be fairest to compare the statins side-by-side.


Sponsors Lightbulb
Old 01-02-2007, 02:53 PM   #2
Join Date: May 2005
Location: Illinois
Posts: 80
TLB50 HB User
Re: Crestor v Zocor potency?

I am sure others are more knowledgeable than me but my Dr. told me that 20 mg of Zocor is about equivalent to 5 mg of Crestor. Difference in side effects, I don't know.

Last edited by TLB50; 01-02-2007 at 02:55 PM.

Old 01-02-2007, 03:11 PM   #3
Join Date: Aug 2006
Posts: 310
Connie122516 HB User
Re: Crestor v Zocor potency?

Personally, I'd never take Crestor unless I'd tried fairly high doses of Zocor and Lipitor first. My understanding is that while the side effects of all three are similar, those taking Crestor have the side effects more frequently. The reason some studies show Crestor does a better job of lowering cholesterol is because it is more potent.

In general, for all meds, the higher the dose, the higher the risk of side effects. In other words, someone taking 40 mg Zocor is more likely to experience side effects than someone taking 20 mg Zocor.

But you can't compare dosages directly between two different meds, i.e. 20 mg Zocor is not the same as 20 mg Crestor. 20 mg Zocor being equivalent to 5 mg Crestor sounds about right to me.

Last edited by Connie122516; 01-02-2007 at 03:16 PM.

Old 01-03-2007, 05:11 AM   #4
Senior Veteran
Join Date: Nov 2004
Posts: 8,479
Lenin HB UserLenin HB UserLenin HB UserLenin HB UserLenin HB UserLenin HB User
Re: Crestor v Zocor potency?

My rule of thumb is pretty much 5 mg. Crestor = 10 mg. Lipitor = 20 mg. Zocor.

Old 01-03-2007, 03:33 PM   #5
Join Date: Aug 2006
Posts: 310
Connie122516 HB User
Re: Crestor v Zocor potency?


The Consumer Reports booklet you have on your website is very good; thanks for letting us know about it. I agree that anyone taking a statin, or thinking about taking a statin, should read it.

I do not interpret their recommendations on Lipitor as having anything to do with safety or effectiveness; they make several statements confirming its safety and effectiveness consistent with what I already know about the studies that have been done. Their recommendations are very reasonable overall, but they put a lot of emphasis on cost factors, which is important but may not be the most important depending upon a person's health condition and financial circumstances.

Lipitor costs more because it does not have a generic (yet). If it worked as well for me as Lipitor, I'd still be taking simvastatin myself. (I actually have fewer side effects with Lipitor...Zocor/simvastatin made me constipated, Lipitor does not). It looks to me like they picked two years mostly out of the air...note they say it assumes you have changed lifestyle issues and have switched to simvastatin.

Note also they do not recommend Crestor for any group of people, presumably because of cost, lack of "proof" that it prevents heart attacks while other statins already have this "proof," and potential safety issues.

Old 01-03-2007, 07:37 PM   #6
Senior Veteran
Join Date: Nov 2004
Posts: 8,479
Lenin HB UserLenin HB UserLenin HB UserLenin HB UserLenin HB UserLenin HB User
Re: Crestor v Zocor potency?


Two months ago at the pharmacist I asked how much of a bargain WAS the simvastatin. I was amazed that it was less than 10% discounted from the cost of the $105 vs. $115. Amazingly the Lipitor in all strengths was just under $100.
The generic simvastatin thus was more expensive than the branded Lipitor.

I asked the pharmacist if that wasn't strange and she said that often it takes many months for the price difference to widen.

When it does, I will probably opt for the cheaper alternative but I have lots of Lipitor stockpiled and partner has lots of simvastatin...we've both been splitting pills for a long while!

Old 01-03-2007, 08:52 PM   #7
Senior Member
Join Date: Mar 2006
Location: houston tx
Posts: 128
mmvic HB User
Re: Crestor v Zocor potency?

The chain pharmacys tend to make their biggest profits off generics and thus, sometimes, the price is not a "bargain". You might try some of the large big box discounters instead of pharmacy chains for better pricing.

Closed Thread

Similar Threads
Thread Thread Starter Board Replies Last Post
constipation from Crestor juan motime High Cholesterol 0 09-17-2009 06:35 AM
experience with crestor? chj High Cholesterol 13 12-31-2006 11:25 AM
Crestor and Zetia jacal5 High Cholesterol 4 11-15-2006 01:48 PM
Crestor question side effects to treat my high LDL ASU1997 High Cholesterol 22 05-06-2005 10:35 AM
Article: Crestor linked to patient death, company says THEM High Cholesterol 13 01-14-2005 04:51 AM
Crestor Warning LV40 High Cholesterol 18 11-20-2004 01:24 PM
Latest results on Crestor rahod High Cholesterol 14 11-11-2004 03:07 PM
Is Crestor "Top Dog"? rahod High Cholesterol 17 08-30-2004 11:57 AM
Crestor Side Effects? don444 High Cholesterol 27 06-28-2004 01:39 PM

Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is Off
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off

Sign Up Today!

Ask our community of thousands of members your health questions, and learn from others experiences. Join the conversation!

I want my free account

All times are GMT -7. The time now is 04:54 AM.

Site owned and operated by HealthBoards.comô
Terms of Use © 1998-2016 HealthBoards.comô All rights reserved.
Do not copy or redistribute in any form!