Overrun,
Those numbers are about what I calculated that splitting a vytorin 10/20 would do with my untreated numbers (that is, hypothetically speaking, you never know who is reading these boards

. I calculated that it would be an average 7% difference (above) my numbers with 10/20 thus would justify using less of both the Zetia and Zocor components. The thing that surprises me about your husband's numbers is the total reduction from 249 to 138. That does sound awfully low but I'm no expert

. My total on 10/20 went from 242 down to 157. So, I would think your husband is getting an extra boost by either diet, exercise, etc.
What I do think your husband's results point to is that using a less dose of the Zetia is not a huge deal as some have worried. In other words, we knew that 10 mg of Zocor is effective and 5 mg of Zetia is (still) giving an even better result (probably the equivalent of taking more of a statin alone).
Anyway, thanks for posting his results. I'll try and do the same in April.