Just trying to cover all my bases and not miss out on any supplement that will help me lower my cholesterol numbers. I know of CoQ10's benefits to the actual heart muscle but does this supplement actually help reduce say LDL numbrs or increase my HDL numbers? Is there any proof?
I deal with cholesterol issues and take CoQ10. My undersatnding is not that it lowers any cholesterol numbers, but that it replaces the CoQ10 our bodies lose when we are on a statin. Has to do with mitosis and production of energy in the cells. I guess the correlation here is that when we produce energy, we can be more active and thus lower our bad cholesterol through more exercise. I started taking it to prvent damage from the statin I am on (you know, like the muscle damage and stuff that is a possible (probable!) side effect). Then the more I learned about it, the more persistent I have become in taking it.
Also deal with consequences of a heart attack (from cholesterol) and the benefits are well known to many with the CoQ10. Blah... what a tangled web I weaved!
I am not taking any statins yet but was wondering if the CoQ10 would help at all. I have read about and knew that anyone taking a statin should always take at the least 100 mg. of CoQ10 per day to alleviate the loss from the statin itself.
Coq10 is an antioxident. It helps cholesterol from becoming oxidized. Cholesterol is only bad when it becomes oxidized. You might not see a change in cholesterol numbers with Coq10, which is not the reason for CoQ10. Rust is a type of oxidation. You don't want your fenders on your cars to rust from the inside out. Kind of like that little Fiat Spyder that I had. It looked great until the rust from the inside came through to the outside. 200 mg of Coq10 is better. 300 if you are on statins.
Do you think that 120mg of CoQ10 daily is too small a dose for someone on a statin? That's what my doc recommended after I had insisted on taking this coenzyme. When questioning the pharmacists about the correct dosage, two thought 120mg was enough, and the others seemed to think I did not need any at all.
I just read a new paper today. It is suggested 300mg per day. I have talked to Dr. DiMauro, (a Coq10 specialist) from Cornell, and a director at the ALS center...he suggested 300mg. 600 if you were suffering problems from the statin, as well as getting off of them. The new paper is Mutations in coenzyme Q10 biosynthetic genes.. DiMauro, depart of neurology, Columbia University Medical Center...(2007). You might also be interested in an article...Statin Therapy Induces Ultrastructural Damage in Skeletal Muscle in Patients without Myalgia. Myalgia is pain. Seems that statins cause cholesterol to remain inside the muscle fiber cells, (and possibly others). Unesterfied cholesterol inside of cells can damage and will eventually kill cells. This is the problem in Niemann-Pick disease. These people eventually die from the cholesterol buildup inside of their cells. Even though many of them have low serum cholesterol, the cholesterol is building up in side of the cells. Seems that statins can cause the same problem. The statin researchers never bothered to check where the cholesterol was going, just that you numbers dropped. Zetia works on the NPC1L1 gene. This was recently reported...but I bet they knew it all along. This gene also causes Niemann-Pick.
These articles sound interesting and I'll look them up. I read the one you'd recommended about a study regarding the connection between low cholesterol levels and violence and found it disturbing.
We have to get informed and stay informed. Knowledge is power.