Re: CoQ10 and lowering cholesterol
I just read a new paper today. It is suggested 300mg per day. I have talked to Dr. DiMauro, (a Coq10 specialist) from Cornell, and a director at the ALS center...he suggested 300mg. 600 if you were suffering problems from the statin, as well as getting off of them. The new paper is Mutations in coenzyme Q10 biosynthetic genes.. DiMauro, depart of neurology, Columbia University Medical Center...(2007). You might also be interested in an article...Statin Therapy Induces Ultrastructural Damage in Skeletal Muscle in Patients without Myalgia. Myalgia is pain. Seems that statins cause cholesterol to remain inside the muscle fiber cells, (and possibly others). Unesterfied cholesterol inside of cells can damage and will eventually kill cells. This is the problem in Niemann-Pick disease. These people eventually die from the cholesterol buildup inside of their cells. Even though many of them have low serum cholesterol, the cholesterol is building up in side of the cells. Seems that statins can cause the same problem. The statin researchers never bothered to check where the cholesterol was going, just that you numbers dropped. Zetia works on the NPC1L1 gene. This was recently reported...but I bet they knew it all along. This gene also causes Niemann-Pick.