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Old 02-25-2005, 08:56 AM   #1
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Diovan raising bp ?

I started taking Diovan 80 mg a few weeks ago. My bp has actually been creeping up a little. It if it creeping up on 80 mg, will it do the same on 160, or will 160 perhaps do the trick? My mom's bp is very love on Diovan 80 + lasix, but I want to keep it to one drug if I can. I've taken maxide, cardizem, toprol, and others and had side effects and minimal reduction in bp. At least the diovan has no side effects so far. Zuzu, I think you said going to 160 might do the trick? Going back to doctor next Tuesday.

Meanwhile, I went to orthodontist Monday and have had pain all week AND a cold, had to break down and take pain meds and even a Sudafed, and that is probably not helping my bp. Also took cataflam last week for menstrual pain.

 
Old 02-25-2005, 10:16 AM   #2
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Re: Diovan raising bp ?

Don't take stuff with decongestants in them. That is the one that causes bp problems.

Maybe increasing the dosage of Diovan will bring down your bp.

My body reacts oddly. If I increase a dosage of a bp med (except for clonidine), my bp actually goes up.

 
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Old 02-25-2005, 03:13 PM   #3
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Re: Diovan raising bp ?

Pain AND a cold PLUS decongestant, is enough to make your BP creep up! One of those ALONE could do it.
Also if one of the pain meds is ibuprofen, that can elevate your BP as well.

Don't fret yet. 80mg Diovan wasn't enough to bring my BP down to acceptable levels- it hovered at 140/90 (having orig. been at 158'ish/high 90's). 160mg did the trick.

I so understand you wanting to be on monotherapy and not have to introduce a 2nd drug. If you do eventually titrate up to 160mg and still need help, a low dose of HCTZ is often a great combo.

zuzu xx

 
Old 02-28-2005, 09:09 AM   #4
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Re: Diovan raising bp ?

I know that sudafed and NSAIDS are a no no for bp, but my gyn and gp have both told me that occasionally taking them won't hurt too much. Sometimes you just gotta function, and last week there was no way to do so sans pain and cold meds.

Is it safe to break the Diovan in half to titrate up?

I've taken Maxide in the past, and I really hate being beholden to a diuretic. Thought, I do notice that the Diovan seems to make me urinate somewhat more often than when I take no drugs, it does not make me have fluid retention. Once I weaned off the Maxide (or trmterene/hctz), I stopped having water retention. Also, I am very afraid of hctz because my mom is very allergic to sulfa drugs, I have had a mild reaction in the past, and there is much more awareness these days of bad sin reactions like Johnson Stevens syndrome, which are most prevalent with sulfa drugs.

Hope that all makes sense.

 
Old 03-03-2005, 09:23 AM   #5
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Re: Diovan raising bp ?

Is it safe to break the Diovan in half to titrate up?

 
Old 03-03-2005, 10:35 AM   #6
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Re: Diovan raising bp ?

Evelyn,
You can break one in half to titrate DOWN, but you won't get much out of 40 mg. (unless you mean to take 1 1/2 to get 120 mg...that would be perfectly ok.)

Next topic: Sulfonamides...Lasix is every bit as similar as thiazide to the sulfonamides so if your mom is happy with the lasix, there's no reason to assume you'll have trouble with either.

You sound like you might be a SALT SENSITIVE "V" type hypertensive. We don't get lot's of help from ARB's but DO get good results with diuretics...with or without the ARB's.

Why not try your mom's dosage and see what you get.

Of course, if you;re worried about sensitivity be on the lookout for the warnings like hives, swelling lips, tongue, tight throat, or rashes that might indicate an allergic reaction. I think the chances are quite slight!

Right, if you gotta have a decongestant to breathe, well then, so be it...some days BEG for a pseudoephedrine (a LOT cheaper than SUDAFED)

Last edited by Lenin; 03-03-2005 at 10:36 AM.

 
Old 03-04-2005, 07:59 AM   #7
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Re: Diovan raising bp ?

Yes, I am salt sensitive, but Maxide has not lowered my BP significantly. Also, I notice that I have rebound fluid retention when taking a diuretic.

I was going to try titrating up to 120 with the Diovan before going to the full 160.

 
Old 03-04-2005, 08:04 AM   #8
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Re: Diovan raising bp ?

Oh talk about REBOUND. If I get to "dry weight" and stop the thiazide for 2 days I fill up like a water balloon.
They do have that "addictive" quality.

I find that they work best if I DO take the occasional day or two off...WHEN I get back to them, but that second day can be tough sledding unless I restrict my salt.

 
Old 03-07-2005, 08:25 AM   #9
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Re: Diovan raising bp ?

I went to doctor last week, upped Diovan to 160 MGs I think last Thursday. BP has not come down. This is after taking Diovan 80 mg for nearly 3 weeks. I have to go and fill prescription, and I'm wondering if instead I should ask for a different ARB. Or do I need to try adding trmterene/htc (Maxide) instead? I have a bunch of the diuretic, but I don't like taking it. in addition to having to go to the bathroom a lot, it makes me feel generally bad.

 
Old 03-07-2005, 09:54 AM   #10
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Re: Diovan raising bp ?

Same thing happened to me. Diovan 80 mg wasn't lowing my pressure enough..It was oivering at 150/90... so we uppped it to 160mg. My one week follow-up showed only a minor dip of no consequence...The doc said "let's give it another week" before adding anything.

Sure enough, waiting two weeks resulted in the difference we were hoping for. BP down from 150/90 to 120/80.

And by the way, one month later, @160mg, BP was down even more...to 117/70 in the doc's office, where, as you know, it's almost always higher than when taken at home.

Bottom line, it might not hurt to wait another week before deciding to introduce another drug or switching ARBs.

 
Old 03-07-2005, 10:17 AM   #11
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Re: Diovan raising bp ?

Thanks Zuzu. I'll hang in there a while longer. No side effects, so won't hurt to wait. Thanks again.

 
Old 03-07-2005, 10:25 AM   #12
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Re: Diovan raising bp ?

Oh, one last question. Does the amount of drug that will affect bp tend to depend on body weight? My weight is normal technically, but I have definitely gained about 15 pounds over the years that I would prefer not to be carrying. I'm wondering if I shed some pounds if less drug would do the trick.

 
Old 03-07-2005, 12:19 PM   #13
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Re: Diovan raising bp ?

15 lbs above "normal" for your height and build should not make a difference.
Hang in there!
Fingers crossed all goes well, since the ARBs are virtually side-effect free for most.

zuzu xx

 
Old 03-08-2005, 07:49 AM   #14
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Re: Diovan raising bp ?

Zuzu

How long does it typically take for ARBs to kick in, and does that mean if you went off of them later it would take a while to tell if your bp were going to rise again?

 
Old 03-08-2005, 08:30 AM   #15
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Re: Diovan raising bp ?

I've heard and read that maximum effect might take up to 4 weeks. Not sure how long, once discontinued, it takes for effect to "wear off".

I tried going off Diovan a couple of times (just for fun (LOL) to see what would happen) and my BP stayed gorgeous for ten days...but then I got chicken and decided to discontinue my experiment.

zuzu xx

 
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