Lenin

aspen,
I took it for 2 periods, the first for a couple months (then known as the brand drug, CORGARD.) WOW, was it a powerful beta blocker...I took 40 mg.

It got so bad, I could bearly climb a flight of stairs without my thighs giving out. AND it has a half like of 3 days so once you have too much in your system it STAYS too much for an uncomfortably long time.

I think plain old propranolol is the best for migraine profylaxis but if you CAN find a tiny dose of nadolol that works, then it has the advantage of long term efficacy, whereas you have to pop MANY propranolols. On the other hand, propranolol is unique in crossing the blood-brain barrier.

What small dose of nadolol is your doctor talking about, 5 or 10 mg.?

Anyhoo, there are a HUGE pile of beta-blockers you can try til you find a happy medium of effectiveness without fatigue.

I take 40 mg. propranolol to stem a vascular headache BUT I really must take it when I feel the aura...waiting for the head-cracking pain is too late and then I need the BIG GUNS: ergotamine or Sansert. I get them too infrequently to consider daily profylaxis.
I think the beta-blockers are a really good choice IF someone has both migraine AND hypertension, angina, or tachycardia.

Let me know how the nadolol works.