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Old 07-20-2008, 12:45 PM   #1
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How long until Diovan is out of system?

Hello,

I started Diovan 160 mg several weeks ago. After 2 weeks, I just could not take it any longer. I was so tired I could not function. I literally had to pull over while driving once because I thought I might fall asleep at the wheel. I was in a fog and I could not take another day. I couldn't work out...didn't want to do a thing. I just stopped it on my own and within a day..I was feeling like my old self. I didn't realize how good I felt before! I don't know if I should have stopped it like that but I did. I have not let me DR. know yet. My readings have been pretty good since I came off. I didn't even see a difference in my BP while on the med and at times it seemed to be higher than usual. I also just got my echo and EKG results and both are good.

It's been 5 days since I stopped. I am still feeling light headed at times and I never had that before taking the medication. It also seems to have exacerbated my MS symptoms. I have very mild MS for over 15 years. My only symptom for years now, was numb fingertips. After 4 days on the medication I had numb hands. My hands are still numb...maybe slightly better...but not alot. It seems too coincidental that it happened after taking the medication to blame it on something else.

I would think that the med would be out of my system pretty fast since I was only on it for 2 weeks. Appreciate any info on this subject. Thank you!

 
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Old 07-20-2008, 03:24 PM   #2
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Re: How long until Diovan is out of system?

hello, I don't know how long it stays in your system, but I've been on diovan hct 80-12.5mg for 2 years and it never gave me any symptons. My pressure is in the normal range. Why are you taking a high dose? I skipped one day taking mine and my pressure went up to 170/100. If you stopped taking it be sure to check it every day! kennyc

 
Old 07-20-2008, 07:15 PM   #3
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Re: How long until Diovan is out of system?

Hi Bon,

It may take longer than two weeks to get Diovan out of your system. These drugs are considered toxins by the body so some of the drug maybe stored in one's fat tissue to be released slowly.

Hand numbness is listed as a side effect of Diovan according to my drug book. It should go away eventually. When I was on Norvasc, the piersing headaches took 2-3 wks to go away & I had only been on it a 2-3 days.

It would be a good idea to make sure you keep your fluid intake up while the drug is being eliminated. Just sip some water etc thoughout the day. Don't drink a lot at once because that will raise you b/p. Diovan maybe hard on the kidneys because the info says to drink plenty of fluid & monitor kidney function.

I couldn't find any info saying not to stop Diovan suddenly. Since your b/p is alright now, it sound like you might not need it. Just make sure you have your monitor checked for accuracy & you keep a log of your b/p's. Fam

Always pick up a package insert about any drugs you are planning to take even if you have to go to another pharmacy to get it. Fam

 
Old 07-20-2008, 07:58 PM   #4
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Re: How long until Diovan is out of system?

Bon,

You don't say how high your blood pressure is without any medication.

Your Diovan rx indicates a need for an antihypertensive. No medications come without any side effects. You have to find one that you can live with and whose side effects do not change your quality of life drastically. Luckily, there are many to choose from. I tried Diovan (and Micardis) and cannot take either, due to severe allergy to this class of drugs. One setback does not mean I am willing to live without any blood pressure medication at all.

If your hypertension goes uncontrolled, your organs and blood vessels could sustain irreversible damage. You could also suffer a heart attack or a stroke and die or become disabled. You should give some thought to the possible adverse outcomes/consequences of living with uncontrolled high blood pressure. When you do, you will realize that putting up with some unpleasant side effects of medication, which helps prevent the occurence of these adverse events, is a relatively small price to pay.

You and your doctor should decide which antihypertensive to try next. It takes a while to find one that's right for you.

flowergirl

 
Old 07-26-2008, 03:45 PM   #5
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Re: How long until Diovan is out of system?

Thank you all for your responses and sorry for my late reply.

Since I have been off of the Diovan, my BP has been averaging in the mid/ upper 120's over 70's to 130's over upper 70's or 80's. On occasion it is in the teens and rarely the 140's or 150's.

I have white coat syndrome terribly...<removed>. As soon as I get in the car to drive to the Dr., I feel my heart pounding and my blood pulsing through my veins. In the Dr. office..my BP goes into the 160's. I was on a 24 hour monitor and there was something wrong with the cuff. It inflated so tightly that my arm and hand turned blue and my veins liiked like were about to explode. It was literally painful and everytime I heard the beep that it was about to inflate..my BP went through the roof in anticpation. I finally took it off so I could sleep. So..that is what my Dr went by..the reading in his office and those results. He handed me samples of Diovan 160mg and said..see me in three week. That was it...no explanation about why that med was chosen, nothing about possible side effects...not a thing. I know I can do my own research, but don't you think a DR should spend a little time discussing this? Especially with someone like me who was visibly upset abou the step I was about to take. Maybe I have unrealistic expectations.

I take my BP multiple times each day and have done so for several years. I do take this seriously. I actually work in a dialysis unit and see first hand each day what high BP can do.

So, right now I am continuing with a supplement regimen I started and adopting some of the dash diet guidelines. I don't have alot of weight to lose, but I figure that even 5 pounds can help. I spin about 3-4 times a week.

My hands are still numb, my left hand quite worse than the right. I am certain that it had to be the medication, It is just too coincidental. It seems like it might be permanent.

Maybe I am in denial and I have find a new Dr and try another med that is better for me. I do live in fear of ending up on dialysis.

One thing I don't understand if the resting heart rate. I think someone else posted a similar question. Wouldn't a non resting heart rate be more accurate? I rarely sit stll and relax for 10 or more minutes during the day. Wouldn't those blood pressures going up and down be doing the damage?

Sorry this is so long and thanks for listening!

Last edited by mod-anon; 07-26-2008 at 10:56 PM. Reason: removed profession

 
Old 07-26-2008, 10:28 PM   #6
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Re: How long until Diovan is out of system?

Hi Bon,

Quote:
One thing I don't understand if the resting heart rate. I think someone else posted a similar question. Wouldn't a non resting heart rate be more accurate? I rarely sit stll and relax for 10 or more minutes during the day. Wouldn't those blood pressures going up and down be doing the damage?
Non-resting heart rate is not accurate in blood pressure monitoring. Or, at the very least, is not nearly as accurate as the resting heart rate.
The average heart beats between 60-80 times a minute. The blood pressure rises every time the heart beats, and falls when the heart relaxes between the beats.

The up and down variations of mean arterial pressure are a result of a distinctive throbbing nature of the cardiac output. The pulse pressure is determined by the stroke volume and a resistance to the flow in the arteries.
Many physical factors influence the arterial pressure -such as the heart rate, fluid volume, resistance and the thickness of the blood, circadian rhythm... All these physical factors are in turn influenced by many physiological factors -exercise, obesity, diet, existing diseases, stress, emotional highs and lows, alcohol consumption etc. Each individuals's arterial pressure response to these physiological factors varies. This results in a moment to moment variations in blood pressure. The heart rate - the pumping action of the heart- is also affected by many factors, such as a level of activity and stress, and fluctuates. This is why it is not a good idea to measure your blood pressure UNLESS you've been at rest for a few minutes.

For the above reasons and due to the continuous changes in blood pressure and heart rate, the best time to measure resting heart rate is in the morning, before getting out of bed. They recommend measuring one's blood pressure early in the morning as well-when fully rested after a previous nights' sleep, and again at night after the day's activities are over and the body slows down. The natural variations in blood pressure throughout the day are considered normal and harmless. For some people, blood pressure variations of up to 40 points are normal. For most of us, the fluctuations in blood pressure are not nearly as high.

Unless you cannot control your blood pressure, you are not in any immediate danger of losing your kidney function. The main thing is to keep the blood pressure down. Not all of the people on dialysis have renal insufficiency due to high blood pressure. There are many other causes leading to ESRD. My kidneys have been damaged by hypertension. Perhaps it was the other way around and the kidney damage has resulted in severe hypertension. It has not been determined. Personally, it is the cardiovascular and cerebrovascular events I fear the most. Worrying about your kidneys, especially if they are healthy, will serve no purpose and will result in needless anxiety. This is bound to be reflected in your blood pressure readings. As our doctors keep repeating over and over, maintaing a good blood pressure control is the key.

Try to learn ways to reduce your anxiety - it could have a negative effect on your blood pressure control. Good luck!

flowergirl

 
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