It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....

High & Low Blood Pressure Message Board
Post New Thread   Closed Thread
LinkBack Thread Tools
Old 08-30-2008, 06:44 PM   #1
Join Date: Aug 2008
Location: arlington,
Posts: 5
ancc70 HB User
Lisinopril and hctz causing high creatine

I am a 70 yr old male active and generally fit. For over 10 years I have been taking 10mg lisinopril together with hdcl and keeping my Blood pressure just fine. Recently I have had a high creatinine level. I have been having some kidney discomfort and am scheduled for an appointment with a nephrologist. I am concerned.

Last edited by mod-anon; 08-30-2008 at 10:27 PM. Reason: starting a new thread with this post.

Old 08-30-2008, 06:52 PM   #2
Senior Member
Join Date: Aug 2008
Location: Baltimore
Posts: 106
Blog Entries: 1
brebre HB User
Re: Hydrochlorizide

Lisinopril put me into acute renal failure. but thank God it was reversible. I am sure that your function will return once you stop this medicine. I developed bad kidney pain and very very dark decreased urine. My creatitine is now 0.9-1.1
Get off the Lisinopril. I now every doctor will tell you it protects the kidneys, but this med will give you kidney failure also.


Last edited by mod-anon; 08-30-2008 at 10:29 PM. Reason: Please use the Quick Reply button to avoid unnecessary quotes.

Sponsors Lightbulb
Old 08-30-2008, 07:31 PM   #3
Senior Veteran
flowergirl2day's Avatar
Join Date: Apr 2007
Location: Canada
Posts: 3,176
flowergirl2day HB Userflowergirl2day HB Userflowergirl2day HB Userflowergirl2day HB Userflowergirl2day HB Userflowergirl2day HB Userflowergirl2day HB User
Re: Hydrochlorizide

How high is your creatinine? How often do you have your kidney function tested? Are you on other medication besides the ACE inhibitor? ACE inhibitor can be extremely BENEFICIAL for most people who take it. This includes people with normal and reduced kidney function. It is also used in diabetic patients with normal blood pressure to prevent a kidney disease, or to stop its progression.

My husband, a diabetic, takes Ramipril to prevent getting diabetic nephropathy. I take mine mostly for high blood pressure, but also to slow down the progression of CKD.


Last edited by flowergirl2day; 08-30-2008 at 07:38 PM.

Old 08-31-2008, 12:02 AM   #4
Senior Veteran
flowergirl2day's Avatar
Join Date: Apr 2007
Location: Canada
Posts: 3,176
flowergirl2day HB Userflowergirl2day HB Userflowergirl2day HB Userflowergirl2day HB Userflowergirl2day HB Userflowergirl2day HB Userflowergirl2day HB User
Re: Lisinopril and hctz causing high creatine


Sorry I did not finish typing the previous post - we had company. They have just left.
You need not worry needlessly and prematurely.
Did you know that there can be many causes of an elevated creatinine level? For instance, you could have kidney stones obstructing your urinary tract. That would also explain your kidney difficulties.
Many drugs affect blood creatinine levels - the diuretics, for instance. You have been taking the Hctz. Some vitamins, such as vitamin C, and some antibiotics also elevate creatinine levels. Other drugs affect the creatinine clearance level or BUN to creatine ratio in some people - captopril, steroids, etc. Eating a lot of beef or other meat 24 hours prior to your blood creatinine test will result in an increased blood creatinine level. Strenuous exercise two days prior to a creatinine clearance test affects the reading. Other causes of high creatinine blood levels are dehydration, gout, excessive blood loss through bleeding in the digestive tract, hypothyroidism, various muscle diseases and conditions. So, you see, even though high creatinine levels could mean some sort of a kidney disease, they are just as likely to be a result of other conditions. (I don't know if this is going to make you feel better???). Who knows, you might have exercised and eaten a t-bone steak afterward on the day before your test.
I would suspect your diuretic. I am on two different ones. They tend to interfere with my electrolytes, urea, cholesterol and other labs. Your nephrologist will rule many conditions out by ordering certain tests. Sometimes a complete kidney workup is all that's needed to clear things up for good. A high creatinine blood level in the context of low creatinine clearance level usually means that not enough creatinine is being removed by the kidneys. Some people can have kidney disease, yet their creatinine level remains completely normal.

Please do not have any sleepless nights over this. I know you will feel much better after a few additional tests. You should be glad a specialist will check you out. He will think of things your doctor could easily miss. One should never rely on the results of a single test. Obtaining identical test results on at least one (or more) other occassion is indicative of a possible irregularity. Did you have your creatine or creatinine tested? It is the creatinine that is measured routinely.


Last edited by flowergirl2day; 08-31-2008 at 12:25 AM. Reason: Adding P.S.

Old 08-31-2008, 08:04 AM   #5
Join Date: Aug 2008
Location: arlington,
Posts: 5
ancc70 HB User
Re: Lisinopril and hctz causing high creatine

many thanks for your thoughts. I do know this about myself ...I will make it much larger than it needs to be and get all worked up before getting all the answers from the pros. Hope you are doing well and thanks again for your thoughts.

Closed Thread

Similar Threads
Thread Thread Starter Board Replies Last Post
Hydrochlorothiazide (HCTZ) over Lisinopril or Micardis for Hypertension? dolby High & Low Blood Pressure 1 07-06-2010 07:32 PM
How Long for results--HCTZ added to Lisinopril? daff High & Low Blood Pressure 5 12-08-2008 04:54 PM
Any Experience with Prinzide (Lisinopril) HCTZ? mrt123 High & Low Blood Pressure 5 05-21-2008 05:21 PM
Serious allergic reaction Lisinopril HCTZ or side effect??? sunshine123 High & Low Blood Pressure 13 03-25-2008 06:51 AM
what can happen if i stop taking lisinopril spoed High & Low Blood Pressure 12 02-07-2008 04:44 AM

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is Off
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off

Join Our Newsletter

Stay healthy through tips curated by our health experts.


There was a problem adding your email Try again

Thank You

Your email has been added

Top 10 Drugs Discussed on this Board.
(Go to for complete list)
Clonidine Cozaar


Machaon (55), atengnr (48), JJ (35), soflsun (29), Flutterbye77 (17), flowergirl2day (16), flitz (16), zuzu8 (15), cartner (12), rudiraven (12)

Site Wide Totals

teteri66 (1180), MSJayhawk (1011), Apollo123 (909), Titchou (856), janewhite1 (823), Gabriel (761), ladybud (755), midwest1 (669), sammy64 (668), BlueSkies14 (607)

All times are GMT -7. The time now is 05:40 PM.

Site owned and operated by HealthBoards.comô
Terms of Use © 1998-2014 HealthBoards.comô All rights reserved.
Do not copy or redistribute in any form!