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Old 11-14-2010, 04:50 PM   #1
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Aspirin and Beta Blocker

I am on 4 different blood pressure medications and my BP is still not adequately controlled. I still get spikes up to 180/90.
I was checking the drug interaction web site and I saw that aspirin and tylenol can make my meds hydralazine and beta blocker not work.
Anybody ever had this problem? I did not know this.
Maybe that is the answer as to why my BP is out of control with 4 bp meds. I am losing weight and my BP seems to be going higher.
The site also said beta blocker and calcium channel blocker should not be taken together.
Any body ever experience this?

 
Old 11-14-2010, 06:59 PM   #2
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Re: Aspirin and Beta Blocker

Many drugs can make your BP go higher, not only aspirin and Tylenol but all forms of NSAIDs...ibuprofen, Aleve, etc.

But I was also told not to take a beta blocker and a calcium channel blocker together because both can slow the heart rate. I was told, one or the other. I recently dropped my beta blocker for a different calcium channel blocker.

What 4 are you on? I had been on 5 and have now gotten down to 3...kind of. Lisinopril, HCTZ and diltiazem....plus potassium. Had been taking a combination beta/alpha blocker that was horrible. Like the diltiazem much better.

Jenny

 
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Old 11-14-2010, 07:19 PM   #3
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Re: Aspirin and Beta Blocker

I am on Imdur 60mg, Hydralzine 50mg three times a day, Bystolic 5mg a day and Norvasc 10mg a day. The side effects are killing me.. I could understand if they were helping my blood pressure. My docs solution is to add more meds. I truly think something is interacting.
The Imdur which is a nitrate used to give me bad headaches and I was taking Aleve like candy but I have not taken Aleve in about 8 days now since I found out it may interact.



Quote:
Originally Posted by jennybyc View Post
Many drugs can make your BP go higher, not only aspirin and Tylenol but all forms of NSAIDs...ibuprofen, Aleve, etc.

But I was also told not to take a beta blocker and a calcium channel blocker together because both can slow the heart rate. I was told, one or the other. I recently dropped my beta blocker for a different calcium channel blocker.

What 4 are you on? I had been on 5 and have now gotten down to 3...kind of. Lisinopril, HCTZ and diltiazem....plus potassium. Had been taking a combination beta/alpha blocker that was horrible. Like the diltiazem much better.

Jenny

 
Old 11-15-2010, 01:15 PM   #4
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Re: Aspirin and Beta Blocker

Brebre,

You have a very strange medication .... Imdur has nothing to do with HBP ....

Do you have a clear picture of why are you taking every medication??

Are you taken anything, even natural remedies, to lose weight?

What about a second opinion??

Jesus

 
Old 11-15-2010, 01:15 PM   #5
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Re: Aspirin and Beta Blocker

So I did some research on a couple of my favorite and trusted sites for drug info. Aspirin, Tylenol and the Nsaids were not mentioned as bad to take but they are known to raise the blood pressure. I take them too and see only a slight increase that I can counter with no caffeine and less salt.

But again, I found the reference to the calcium channel blocker and the beta blocker together. The site I trust the most explained that the 2 together tends to enhance the side effects of both.....probably what is driving you nuts. They can be given together but they will give you trouble.

Your Imdur is not technically a BP drug. It is a nitrate for relaxing the muscles of the heart and stopping angina. And Hydrlazine , although a BP drug is also used for congestive heart failure. So I don't know if either of these drugs is for your BP or your heart.

Are these being given to you by a primary doc or a cardiologist? Have you ever been assessed by a hypertension specialist? That is not necessarily a cardiac doc. I was sent to a kidney specialist who did the evaluation as primary hypertension usually starts in the kidneys. Consider seeing a nephrologist for an evaluation.

I found that by seeing a real specialist in these areas that they changed and adjusted my drugs to make it easier for me to do what I needed to do...exercise and lose some weight. And my primary did whatever they told me to do. Sometimes primaries just don't understand the potency of these drugs and that other combinations work much better.

I take lisnopril(Ace inhibitor), diltiazem(calcium channel blocker), HCTZ(diuretic), and potassium. I'm on the maximum dose of the Ace inhibitor, medium on the diltiazem, low on the diuretic and medium on the potassium. Taking potassium is fairly recent for high BP. My doc didn't quite believe the it but once he put me on it, I have done great. I have always had low potassium even when not on the diuretic and that may be where the trouble starts for me. Eating bananas didn't help....I needed a strong daily supplement....prescription type, not over the counter. Has your doc even checked your potassium?

Seeing a BP specialist has really helped and I can't suggest it enough if you haven't seen one already. I have a family history of malignant hypertension so I am at risk and they take my BP very seriously. But right now, I am at 110/70 most days. Found my "magic bullet" that controls whatever is causing this family problem. Hope you can find yours.

hugs..............Jenny

 
Old 11-15-2010, 06:43 PM   #6
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Re: Aspirin and Beta Blocker

Ok let me explain, I do have heart problems and high blood pressure.
My EF is decreased at 40-45%. I am allergic to Ace Inhibitors and Angiotensin receptors blockers which is very bad.
So my doctor put me on Bidil which a combination of Imdur and Hydralazine. The company sponsoring the trial of Bidil was so great that the trials ended early.
I take the Bystolic and Norvasc for the blood pressure.
I see a Cardiologist that specializes in coronary artery disease. I was thinking of going to a cardiologist specializes in hypertension.

I am about 50 pounds overweight. I have already lost 60lbs so far.
My decreased EF is 100% connected to the hypertension,. Therefore I have got to get this under control.

The beta blocker makes it so hard to lose weight. Thanks for the responses.




Quote:
Originally Posted by jennybyc View Post
So I did some research on a couple of my favorite and trusted sites for drug info. Aspirin, Tylenol and the Nsaids were not mentioned as bad to take but they are known to raise the blood pressure. I take them too and see only a slight increase that I can counter with no caffeine and less salt.

But again, I found the reference to the calcium channel blocker and the beta blocker together. The site I trust the most explained that the 2 together tends to enhance the side effects of both.....probably what is driving you nuts. They can be given together but they will give you trouble.

Your Imdur is not technically a BP drug. It is a nitrate for relaxing the muscles of the heart and stopping angina. And Hydrlazine , although a BP drug is also used for congestive heart failure. So I don't know if either of these drugs is for your BP or your heart.

Are these being given to you by a primary doc or a cardiologist? Have you ever been assessed by a hypertension specialist? That is not necessarily a cardiac doc. I was sent to a kidney specialist who did the evaluation as primary hypertension usually starts in the kidneys. Consider seeing a nephrologist for an evaluation.

I found that by seeing a real specialist in these areas that they changed and adjusted my drugs to make it easier for me to do what I needed to do...exercise and lose some weight. And my primary did whatever they told me to do. Sometimes primaries just don't understand the potency of these drugs and that other combinations work much better.

I take lisnopril(Ace inhibitor), diltiazem(calcium channel blocker), HCTZ(diuretic), and potassium. I'm on the maximum dose of the Ace inhibitor, medium on the diltiazem, low on the diuretic and medium on the potassium. Taking potassium is fairly recent for high BP. My doc didn't quite believe the it but once he put me on it, I have done great. I have always had low potassium even when not on the diuretic and that may be where the trouble starts for me. Eating bananas didn't help....I needed a strong daily supplement....prescription type, not over the counter. Has your doc even checked your potassium?

Seeing a BP specialist has really helped and I can't suggest it enough if you haven't seen one already. I have a family history of malignant hypertension so I am at risk and they take my BP very seriously. But right now, I am at 110/70 most days. Found my "magic bullet" that controls whatever is causing this family problem. Hope you can find yours.

hugs..............Jenny

 
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Old 11-15-2010, 06:46 PM   #7
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Re: Aspirin and Beta Blocker

The natural supplememts I take are magnesium, coenzyme, vitamin b complex, and garlic





Quote:
Originally Posted by jrueda View Post
Brebre,

You have a very strange medication .... Imdur has nothing to do with HBP ....

Do you have a clear picture of why are you taking every medication??

Are you taken anything, even natural remedies, to lose weight?

What about a second opinion??

Jesus

 
Old 11-16-2010, 11:13 AM   #8
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Re: Aspirin and Beta Blocker

With the allergy to the ACE inhibitors and the angiotensin receptor blockers, you are kind of screwed. You are stuck with the beta blockers and the calcium channel blockers. There are also alpha blockers but they are the end of the line for most and rough drugs to take. I was on a tiny amount and it was bad. But I would ask about the potassium levels and the effect on controlling BP. It's a fairly new study and once I convinced my doc to try it, it has made a big difference. Apparently you need potassium to for your heart to work right and when it is even a slight bit low, it affects how hard the heart pumps. They have a range of high and low numbers but the study showed that even a slight drop when you have hypertension is bad...not just below the set level. It should be slightly high if anything.

It takes most docs a long time to integrate new info into treatment. But with my meds I was averaging 135/80 and just adding the potassium brought me down to 110/70. And my level is still slightly low....last test was 3.8. Normal is from 3.5 to 5.5 and my doc wants me at 4.5. It is worth asking about and having your levels checked. I frequently have fallen below 3 and had to go to the ER to get monitored meds. Too little potassium and your heart stops and the same with too much. It is vital to optimal heart function(and all muscles).

It's just a suggestion to try to see if you can get it under better control so you can bring some of those meds down.

I have also lost 50 pounds with 50 to go and did most of it just walking...and walking....and walking......1.5 to 2 hours a day. Good for the heart and good for the weight. Hypertension guy told me longer but less intense exercise is best for the heart muscle. Now if only my knees would let me continue walking. Think I need some revision surgeon on my replaced knees first!

Good luck. Hypertension is a lousy disease. So insidious and so hard to control but so fatal.

hugs...........Jenny

 
Old 11-16-2010, 02:07 PM   #9
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Re: Aspirin and Beta Blocker

I guess I can understand why beta blockers are usually end of the line or for hard to control BP,but why are CCB's always put into that catergory?

 
Old 11-16-2010, 02:46 PM   #10
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Re: Aspirin and Beta Blocker

Brebre,

Let us go to basics, have you suppressed salt intake?

Have you ruled out anxiety as cause of the BP?

What is the heart problem that you have? Indur is for angina, but you reported low EF, What is the diagnostic?

Normally HBP produce left ventricular hypertrophy but not reduced EF.

And, if I am not wrong, calcium channel blockers are not indicated with low EF, they will reduce the strength of the hearth muscle.

Jesus

 
Old 11-17-2010, 06:57 PM   #11
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Re: Aspirin and Beta Blocker

Beta blockers are not "end of the line" hypertension drugs. Alpha blockers are. Beta blockers are used when the heart rate needs to be controlled along with the BP or heart beats that are out of sync like PVC's.

Calcium channel blockers do help with blood pressure but some studies about 15 years ago showed that they don't help to prevent heart attacks and if other drugs could be used, then they should be. But some people just do better on CCB's. They also help to control errant beating problems like PVC's. In my case, they did a better job at stopping the PVC's than the beta blockers.

Neither are "end of the line" but have a different role to play and are used when the heart beat is a problem as well.

 
Old 11-17-2010, 07:01 PM   #12
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Re: Aspirin and Beta Blocker

I have cardiomyapathy with CHF secondary to high blood pressure. HBP will indeed also cause CHF or a low EF.

The treatment my doctor gave me was Coreg. Coreg gave me stroke like symptoms, I am allergic to ace inhibitors. So he decided to try Bystolic since it was a novel beta blocker. I did find out that the FDA failed to approve Bystolic for low EF.
There was a trial drug called Bidil which consists of Imdur/hydralazine. The results were so favorable that they stopped the trial early. I am on Bidil. It is an interesting drug. When you get a chance look it up.
I don't have angina, chest pain and I have never had a heart attack.

I had a ekg, stress test and echo that diagnosed me.

Well anyway I didn't take that beta blocker yesterday(i know i have to wean off of it). My BP was 20 points lower. I know it is the beta blocker cause after I take it I can feel my BP go up. The calcium channel blocker Norvasc lowers my bP. I know the BIdil is working cause I have more stamina.



Quote:
Originally Posted by jrueda View Post
Brebre,

Let us go to basics, have you suppressed salt intake?

Have you ruled out anxiety as cause of the BP?

What is the heart problem that you have? Indur is for angina, but you reported low EF, What is the diagnostic?

Normally HBP produce left ventricular hypertrophy but not reduced EF.

And, if I am not wrong, calcium channel blockers are not indicated with low EF, they will reduce the strength of the hearth muscle.

Jesus

 
Old 11-18-2010, 09:19 AM   #13
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Re: Aspirin and Beta Blocker

That is really interesting that the beta blocker made your pressure go up. You know your body and I congratulate you for being willing to try different things.

In my family, hypertension seems to be from the kidneys. It was kidney failure that killed my grandmother but you end up with the question, did the hypertension come from the kidneys or kill the kidneys. I know my hypertension specialist told me that most primary hypertension comes from the kidney. So he did a renal artery angiogram for starters. And then we "tinkered" with the meds.

However, we moved after that and now my primary does the drug tinkering. But at least he's willing to do it. Some docs are just "my way or the highway" and I actually "shopped" for a primary would work with me and not dictate. That was how we finally found the 4th drug, potassium. I was low and he ordered some and I pushed him to order higher and higher doses and it worked. Helps my primary is an MD, PhD and used to work for a drug company. He was more willing to try things.

I glad you know your body so well. Now to convince your doc that the beta blocker is doing what you say it's doing. Do you do daily BP logs with your own cuff? I did, in order to prove to my doc that the alpha/beta blocker combo was making things far worse. My BP would plunge and then my body would over react and send it higher. The wrong drug for sure.

And even my old calcium channel blocker wasn't doing too much good. But this new one I suggested and then we tried it and it has been great. Better control of my constant PVC's and BP. I have trouble with 24 hour drugs working for 18-20 hours but this one does the job. I get strokes with my hypertension and have had 5 so far...I'm 59 and they started at 48.

Last year I had some TIA's after the mail-in pharmacy gave me the wrong dosage of my drug but insisted it was the right dose. They had changed drug makers and the colors were different....but it turned out I was right because they dropped that drug maker after only a month after they got all sorts of complaints. The drugs didn't have the correct amount of med in them. Sandoz just got a huge fine for that happening in their Puerto Rico plant. So if you ever find that a new script is not working right, take it back and insist on a different brand. You may be very right and it could kill you...almost did me.

I hope you get this under control. Cardiomyopathy is a real bad problem. I get echo's done regularly to watch for it but my enlarged left side has actually gotten almost back to normal size. Need to get back to walking or doing some kind of regular extended low impact exercise.

Good luck and let me know what happens with the beta blocker. I like it when I can learn form others experiences.

gentle hugs..........Jenny

 
Old 11-18-2010, 09:56 AM   #14
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Re: Aspirin and Beta Blocker

OK Brebre,

Thanks for your explanations, unfortunately I run out of ideas that can help you.

Good luck

Jesus

 
Old 11-19-2010, 09:16 PM   #15
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Re: Aspirin and Beta Blocker

Quote:
Originally Posted by brebre View Post
I am on Imdur 60mg, Hydralzine 50mg three times a day, Bystolic 5mg a day and Norvasc 10mg a day. The side effects are killing me.. I could understand if they were helping my blood pressure. My docs solution is to add more meds. I truly think something is interacting.
The Imdur which is a nitrate used to give me bad headaches and I was taking Aleve like candy but I have not taken Aleve in about 8 days now since I found out it may interact.
NSAIDs do negatively impact the function of many antihypertensives.

Have you been worked up for secondary causes of HTN (renal artery stenosis, etc)?

 
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