Originally Posted by sujkap
my husband has henoch shonlein purpura since 2 years,which involves vasculitis on arms and legs, terrible pain in the abdomen, knee joints. He is on methotrexate 12.5 orally weekly, off prednisone at the moment. all other reports, levels are clear, I hope you can deal with your problem. We are still very confused about this illness
I am sorry to hear about your husband. It sounds like we have some similar symptoms. What does the vasculitis on his arms and legs look like? Mine appears as simply small red lumps, essentially swelling just below the skin or at the skin, about the size of a coin and they last 2-3 days before going away. Do your husbands symptoms seem to come and go, for example, lasting a couple of days and then he feels good for several days before the symptoms come back? Or, is he constantly feeling symptoms?
I am on Methotrexate of 15mg per week but the doctor has just increased it to 25 mg per week. My doctor is concerned by the abdominal pain more than anything. I had an MRA (magnetic resonance angiography) that showed mostly normal except for one area of possible narrowing or stenosis of an artery.
The weird thing is that I have been getting the outbreaks of red nodules on my legs for many years, possibly as many as 8 to 10 years but it has slowly gotten worse over the last year or two and now I'm getting additional symptoms such as adominal pains which I never had before this year.
I too am very confused by this condition but I am now seeing a doctor at the Mayo Clinic which seems to be an excellent facility. He has discussed trying something other than Methotrexate should it not help calm down this process. He said there are other medications that suppress the immune system in different ways that could be tried.