Originally Posted by angela72
Cottonsocks - you sure know your immune system and diseases that are problems for it.
With my daughter, she does have JRA (Juvenile Rheumatoid Arthritis - dx at age 22 months) and autoimmune enteropathy. Of course, she also has other problems in a nutshell that are "mysteries" to the doctors for many years.
One MD thinks she may have SLE (system lupus erythmatosus -sp?) - and she has many of the symptoms, but they keep backing away from that one.
I have vitiligo - so does my dad and his sister. I'm not sure of any other autoimmune problems in the family. My vitiligo is extreme, whereas I did not know my dad nor my aunt had it - very mild.
What are some good websites for the immune system?
Hello angela, it is a long time since I last posted, and I apologise for not getting back sooner, so I hope you read this.
I presume by saying autoimmune enteropathy you are meaning Gluten enteropathy? or Coeliacs disease?
I have explained what that is, and removal of the wheat from the diet will remove the resulting irritation from that
, however, if say your child does have lupus also, which was maybe triggered by the gut allergy, it will not rid the person of lupus.
Autoimmunity simply means an abnormal immune response occurring of and to *self.* Within this abnormal immune response, abnormal antibodies are produced, called autoantibodies.
All autoimmune diseases come under the same umbrella of autoimmunity. The manifestation may be different, and the symptoms of that manifestation different, but the characteristics of autoimmunity apply to everybody who has this mutated or faulty gene.
These characteristics are...
1) The manifestation of the abnormal immune response (autoimmune response) waxes and wanes in severity throughout the period of activity
2) remission periods can be of long or short duration, but usually when young. I went into remission for 18 years! A child with autoimmune bullous skin disease, usually returns to normal at puberty. Only 12% of children carry it into adulthood.
3) DIET cannot cure autoimmune diseases- period, Not even those with gluten enteropathy, BUT if say the GE stimulated another autoimmune disease like Dermatitis Herpetiformis, then diet will control it, however the disease once stimulated takes from months to years to disappear, as long as the gluten remains removed from the diet.
4) there is no cure, unless a drug can be found to disable the mutated gene. Foods cannot repair a faulty gene, nor within an autoimmune response
the resulting malfunctioning of the chemically signalling cells of the immune system. The goal of treatment is Control, enough to suppress the disease, yet have a viable immune system.
5)A person can have more than one autoimmune disease
6) Only people who have this genetic predisposition to autoimmunity can have these diseases, however they are not all hereditary, unlike psoriasis or diabetes. Hereditary disease is a genetic predisposition to a specific disease itself.
7) Autoimmune disease can be idiopathic (occurring of self, spontaneously and for no apparant reason) or stimulated by non-self factors, which the person has a definate allergy to, such as gluten, certain drugs, chemicals. These are known as enviromental factors. These may trigger the already present genetic predisposition, (and always will be) but once removed from ingestion, the autoimmune response will not occur again, but it takes time for the manifestation to disappear.
Please note that anybody with an autoimmune bullous (blistering) disease of the skin, can be in danger of that disease going into the eyes. Upon diagnosis with a bullous disease, the person must be sent to a corneal specialist, so that that door remains open for them , should they need it. These conditions are rapid in these tissues, and regular checks must be made, because symptoms often are not noticeable until the disease has already caused serious damage. I lost my sight totally due to this.
If you just ****** for "understanding immunity" there are lots of sites, some with very simple explanations of how cells of the immune system interact with one another, and with diagrams. Please remember though that when reading it is about a normal immune
response to non-self factors (outside the body). To visualise an abnormal autoimmune response, think of the cell being shown of an antigen, as that being one of *self* ( of the inside of the body.)
I am not sure whether it is allowed to leave a link to a site explaining the cells of the immune system, but this one is good easy one to understand. http://nobelprize.org/educational_ga...ne-detail.html