High serum Iga and low igm
I'm new here. I'm 38 yo and healthy in general. 4 years ago I got sick with throat and respiratory infection which turned out to be viral (virus was not identified). After 4 days of very high fever extremely soar throat, and coughing, I was hospitalized for 7 more days. the main suspicion was lymphoma since many of my lymph nodes were very swollen, but a CT ruled that out. The Ct also showed an abnormal pulmonary infection. The only rare finding was a poly-clonal hyperglobulinemia of very high IGG (2600) and IGA (1570). after a few days i got better and sent home. ever since i did not get sick again for 4 whole years. last month I had a regular blood test and the results showed high level of total protein (8.6 mg/dl where 8.2 is upper limit) and globulin (4.2 where 3.5 is upper limit). further tests (immuneglubolins/fixation) showed that my IGA level where very high at 860 mg/dl where upper limit is 400 and low levels of Igm (32 mg/dl) where lower limit is 45. The Igg levels are normal within range.
it seems that the high level of globulins are still poly-clonal and consists of both kappa and lambda light chains (both very high with k/l ratio of 2, within range). electrophoresis test showed that all other globulins (Gamma, Alpha1/2 and beta) are within normal ranges
Since I do not have any other symptoms, my doctor referred me to an immunologist for which i have an appointment for next month.
Could the unknown infection i had 4 years ago messed up my entire immune system? am I in any danger of developing something more serious? could this be a begging of something malignant.. ? is this the end...?
Thanks and sorry for the bad English
Last edited by EB1000; 09-05-2010 at 12:16 PM.