Well I am at my wits end! My 7 year old has been to the hematologist, the dermatologist, the cardiologist, the rheumatologist , the allergist and none seem to know whats wrong with her! It started with a rash on her thighs ( erythema multiforme) the PCP diagnosed it, then it goes away so i thought it was a reaction to maybe a medicine she was on for a cold or something. 3 weeks later it came back, spread to her calves. It has been doing this for 2 years. It is now on her thighs, calves, hands, arms, ankles, feet, and underarms or and her lower belly and back. It is not on her chest, face upper back or butt. It does not itch her. ASO titer was 1280, previous test 3 months back titer was 637. ESR and CRP were a little elevated but within "normal range" . She also has a low positive ANA 1:40. They send me to cardiologist who says nothing wrong with her heart. Rash biopsy from dermatologist came back non specific rash. Allergy tests revealed nothing. I am so lost! She does complain from time to time this hurts or that hurts but nothing horrible like she cant get out of bed. I just want to know whats wrong. Its so complex for her because its all over she dont wanna wear shorts or a dress, short sleeve shirts. Anybody can help~!?