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Irritable Bowel Syndrome (IBS) Message Board
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Old 09-07-2003, 04:07 AM   #1
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Post Trends in Blood Tests


This is basically a poll of IBS sufferers. Weve all taken a lot of blood tests, has anyone found any values that are out of the normal range?

Personally, despite every test ive undertaken, I have high levels of: Globulen & Proteins in my blood which are normally associated with chronic infection or inflammation.

In my case, the doctor and I have exhausted every possible avenue over several years, with no success. But has anyone else had something in their blood tests that is still an Unsolved Mystery? (Maybe it is IBS related..)

 
Old 09-07-2003, 06:09 AM   #2
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adso,

Of course many things could cause infammatory markers to show up in the blood, but among the suspects, I'd put some colitis involvement that is perphaps CAUSATIVE of the irritable bowel.

Usually the term IBS is used for non-inflammatory conditons though there's no reason a person couldn't suffer from both (other than definitional.)

Do you ever have mucous or bleeding...they're usually colitis markers.

 
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Old 09-07-2003, 02:59 PM   #3
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Blood values that would be elevated in cases of infection and inflammation are normally:-

CRP (C-Reactive Protein) which indicates infection in the body.

Raised white cell count which indicates a bacterial infection within the body.

Raised Sed Rate which indicates inflammation within the body.

IBS is not a pathological disease in that sense of the word, so this is likely to be linked to something else somewhere in your body that is going on.


 
Old 09-08-2003, 01:21 AM   #4
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Thanks for the responses.

Ive had all Inflammatory Bowel Diseases (IBD) ruled out already. No bleeding or anything. Just continually high Gamma Globulin (Protein) levels, year after year, which supposedly indicates inflammation or infection. My Hematologist has run out of tests to give me, so im just living with it.

Youre right, in that it can definately be caused by numerous things. But I guess IBS by its very definition should not be causing an inflammation, else it would be called IBD instead! I like that logic!

 
Old 09-08-2003, 04:23 AM   #5
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The fact that you have persistantly raised Gamma Globulin levels actually relates to your liver rather than any other organ of your body.

If I were you, rather than seeing a hematologist, it might be worth your while going back and seeing a Gastroenterologist again and one that specialises in liver diseases too.

It is just that a raised Gamma Globulin level can indicate infection, past or present or that you have at some stage come into contact with Hepatitis A. Gamma Globulin is the vaccine that is given as short term protection from Hep A before travel.

If I were you, I would strongly suggest that you go and get some more tests run on your liver and get full liver enzymes done just to check.

You said that you levels have been raised for about a year? In this time, have you travelled anywhere where you could have come in contact with Hep A or have you had a vaccine for Hep A?

This is worth investigating further though and maybe you could get to the bottom of it. As I said before, it is not likely to be linked to IBS as being a syndrome there is no inflammation present as in cases of IBD.

Good luck

 
Old 09-09-2003, 08:14 PM   #6
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Thanks for the input Sarah, I will try and investigate possible liver issues as a cause.

Basically its been 3 years with the same gamma globulin levels, luckily they arent rising any higher, meaning theres is nothing getting any worse.

I have never done any travelling though, I have heard that with Hep A, the gamma-globulin injections can be given to raise anti-bodies and fight off any infection, nothing like that in my case though.

Thanks again, atleast I can rule out IBS. Sounds like im in the wrong forum on this one

 
Old 09-10-2003, 12:34 PM   #7
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OK, What about elevated IgG antibodies and normal to high levels of IgA in the blood. This appears to be a stomach reaction to something foreign, if i interpret the antibodies correctly.

 
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