Hi im new to this site, i was diagnosed with ADPKD around age 5, i have full function of both kidneys but suffer from ALOT of pain in both sides. Ive been taking a combination of Endone (Oxycodone) and Tramadol, but lately its built a tolerance and the pain is worsening. Im keen to hear from others with ADPKD, and how its affecting you? Im so miserable lately, its getting me so down being in constant pain and knowing it will never get any better