OH lord I tried these a few times and will never do them again. I've had so far 7 knee surgeries and these treatments, cortisone, etc etc.........I've tried everything just waiting till the doctors think I'm old enough to have TKR.
Matter of fact I'm calling them tomorrow and seeing if 43 is old enough as I would really like to enjoy walking and sleeping without pain while I'm still "young".
Hopefully they will work for your wife but they sure didn't do anything for me except make me scream
each time they injected my knee. I'm a big sissy with injections in the joints and had to have a valium and my husband to go with me the second and third time. So I will say go with her to hold her hand if she does decide to do them - ouch ouch ouch!! Now I will say I have ZERO cartlidge left in my knees so they say that makes it hurt worse.
ps.......they are called Synvisc injections if you want to google them