I also use a vaginal estrogen cream to aleviate severe vaginal dryness. The only thing that I have is I get a bad case of the munchies, like I used to just before and the first few days of my menses. When that happens I know I have forgotten to use it the way I should. You see my husband is a long haul trucker so this isn't an everyday problem. I would probably remember to use it regularly if he were home more.
Are you still using the cream or have you discontinued it? The concentration of estrogen is very low in the cream. Perhaps it is something else in the cream causing a reaction. Good Luck.
May God Bless You