Your post actually has two parts.
First, Ativan. Any antianxiety med is going to make you dopey at first. That is their purpose: to calm you down. Sometimes it is too strong for people, but sometimes they just haven't let their system adapt to it. I started this journey with Ativan and thought I couldn't stand it. I'm now on all sorts of downers in the forms of antianxiety meds, pain pills, muscle relaxers, etc., and I stay awake just fine.
Secondly, the antidepressants. One day of an antidepressant isn't going to do anything. Most antidepressants take 4-6 weeks to have an effect.
Even once the meds take effect, the doctor may have to adjust ("tweak") them until it's the right fit for you. The same med can work very differently in different people, and even in the same person at different times. It takes patience to work with both of these kinds of meds. Be sure you have given them a long enough trial before you write them off. Also, many people with lupus need psychotherapy or counselling to learn new coping skills to adapt to their illness. You may find this beneficial along with the Ativan. I know I did!
I have to go now and retrieve my cat, who seems to want to climb up the inside of the curtains with no claws. Talk about frustration!