JAC61, Lupus is so complex! Maybe it's better to read some, then hit your dr. with specific questions. There are hardcovers in most libraries & bookstores by two Americans, (1) Dr. Daniel Wallace, and (2) Dr. Robert Lahita.
Also, there are some fine links available from this Board. (1) Open the "sticky post" at the top of the thread list, the one about test results. The link you'll find there has a whole series of articles by a top East Coast rheumie. (2) Also, the "Resouces" tab above can take you into vrs. medical-info sites. e.g., choose MedLine Plus, then Health Conditions, then Rheumatology, then Lupus.
Since reacting to Prednisone & Plaquenil, are you taking any "disease modifying" lupus drugs, or just pain relievers? Was the Plaquenil generic or name-brand? I've read various people reporting that they reacted to the generic (hydroxychloroquine) but did better on the brand-name. Bye for now, Vee