Originally Posted by Dj1Chickee
I am very curious to know how many of you Lupies here on the board have family members who also have been diagnosed with Lupus. The reason is that I have so many in my family that have.
My father had Lupus (deceased), I have Lupus, my daughter has Lupus, my sister (she is my only sibling) has Lupus, and her daughter has Lupus.
Is there anybody else out there with family members who have also been diagnosed with Lupus?
Wishing You All Pain Free Days,
Wow, that's a lot of people with lupus in one family.
My father had lupus, my sister has lupus and my father's sister has lupus but her case is very mild. Her children are grown and neither has any signs of lupus. My father had three siblings, so two out of four had lupus.
I'm not diagnosed with lupus although I have positive ANA and several symptoms, but I probably have some kind of arthritis and/or connective tissue disease, which is not definite enough to be diagnosed yet. I know there is a genetic link and I worry about having children, but from the literature I've read, it's really not supposed to be that much of a risk.
From what I've read, if one identical twin has lupus, the other will develop it in more than two-thirds (69%) of the time, but if the twins are not identical the likelyhood is only 5%. Overall, only 10% of people with lupus have a family member with lupus according to a study made in 1994 (McKann).
So it looks like your family and mine (although less so) is different from the norm. I know that the heridity of lupus is being actively studied and hopefully something will come out of it.
There's supposed to be some sort of environmental trigger (otherwise identical twins would always both get lupus), but I don't think anyone knows what it is. In my family, neither of the women with lupus had hysterectomies or other major surgery prior to getting sick and there's nothing specific I can point to that triggered their illness.
Wishing you and your family all the best.