I had trougle with active lupus for years but it seemed to go into remission about 8-10 years ago. During a routine blood work up they did an ANA test and it came back with a titre of 2645. I don't have any of the old Lupus symptoms and really have felt pretty good. My sed. rate was also normal. Does anyone have any ideas as to why the titre would be so high with a low sed. rate?