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Angie10 · 01-09-2009, 01:19 PM

Hi everyone,

I started Methotrexate a month ago and am now up to 10 mg. every Friday. I was taking 1 mg. of folic acid every day. Last Saturday I felt so tired that I barely wanted to do anything. Sunday was even worse. This past week has been brutal and I've been eyeing the clock all day, waiting for work to end.

Has anyone had this type of problem? Could my B12 be on the low side? I just started taking 2 folic acid pills yesterday and it has helped with the nausea and stomach pain, but I still feel so run down - like I'm getting over the flu.

Thank you for anything you can share!

Shaymari · 01-20-2009, 01:35 AM

Make sure to have your thyroid checked since methotrexate can interfere with it. I was on methotrexate for four years and have hypothyroidism from it. Now I am on Cellcept with really great results. Good Luck and I hope you start to feel better soon.

Angie10 · 01-22-2009, 02:35 PM

Hi Shaymari,

Thank you for the information about the thyroid. I am actually going in for a thyroid bloodwork soon because my heart rate was elevated at my check up. I will also look at other medications. The Methotrexate wipes me out and it makes going to work every day a real challenge. Wish I could take a midday nap!

Take care!

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