It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Lupus Message Board
Post New Thread   Closed Thread
LinkBack Thread Tools
Old 04-06-2009, 12:03 AM   #1
Newbie
(female)
 
Join Date: Oct 2008
Location: Australia
Posts: 7
hayleyjohnson HB User
Lupus in the family

My Maternal Grandmother had lupus. I didn't know much about it as I was young when they used to talk about her "wolf in sheeps clothing" disease... My Mum tested positive several years ago but was told it was laying dormant at the time. My sister recently watched a show about Lupus, in which she learned that there is a test which is more accurate for testing for Lupus - that many people have tested negative to the standard blood test and then tested positive with this test.

I have been tested, as my GP believes that although a genetic link has not been proven with this disease, hereditary evidence is more important - my sister would like to take the more trustworthy test, but is unable to remember the name of it. I am sorry, I know I have not given much information, but if anyone knows what I am talking about, help would be appreciated!

 
Old 04-06-2009, 06:30 PM   #2
Junior Member
(female)
 
Join Date: Aug 2008
Location: Dallas, TX, USA
Posts: 16
klbk HB User
Re: Lupus in the family

Maybe they mean the double-stranded DNA test. It is more specific than just the ANA test.

However, there are many components to a diagnosis of lupus, so it's not that easy.

Good luck!

 
Sponsors Lightbulb
   
Old 04-08-2009, 04:42 AM   #3
Facilitator
(female)
 
Join Date: Feb 2004
Posts: 4,907
VeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB User
Re: Lupus in the family

Hayley, hi & welcome! As klbk posted, lupus is a multi-faceted diagnosis, based on more than a single test or genetic history. There's a "sticky post" ( = permanent info post) at the top of the thread list with the accepted diagnostic criteria. You typically** must meet at least 4 of the 11 at some time (meaning not necessarily all at once), to be Dx'ed with systemic lupus. Think of checking off each criterion you've met, in indelible ink.

** I used the word "typically" because I've read that people are occasionally Dx'ed based on fewer than 4 criteria. The criteria met are no doubt the HUGE ones (I think). As klbk wrote, anti-ds-DNA surely is a "biggie", as it (and anti-Sm) are viewed as exclusive to lupus. Either of those coupled with, say, a high ANA &/or protein in the urine would probably raise a huge red flag to a doctor, even when 4 criteria haven't yet been met.

More thoughts: (1) ANA is only a threshold test; and it's positive in multiple diseases & conditions (not just lupus), or even due to a family tendency, a passing virus, aging, etc. (2) Lupus is not considered heritable, strictly speaking. That said, autoimmunes can cluster somewhat in families. e.g., my sister has a thyroid disease; I have lupus. (3) Some people have some mild "positives" in the specialized bloodwork yet are otherwise asymptomatic, meaning have no "clinical symptoms" like fatigue, joint pain, etc. I think drs. tend to monitor, to see what (if anything) happens next.

Hardcover books written by rheuamtologists discuss SLE in great detail. I don't know names of Australian rheumie/authors (sorry). Here are a few I do know of: Dr. Graham Hughes (U.K.); Dr. Daniel Wallace &/or Dr. Robert Lahita (both American).

If your sister remembers which TV station she saw the show on, maybe you two could contact the station for specifics? Let us know how you all are doing, when you can. Sending best wishes, Vee

 
Closed Thread

Similar Threads
Thread Thread Starter Board Replies Last Post
Lupus and H1N1 Vaccine (I can't believe this)... TisJustMe Lupus 10 11-20-2009 09:33 PM
Hereditory Link To Lupus ??? topsy123 Lupus 8 07-08-2008 02:22 PM
Having Babies with Lupus? Lilz Lupus 5 05-05-2007 03:59 PM
Family members with Lupus? Dj1Chickee Lupus 4 04-22-2007 08:50 AM
could it be Lupus???????? Jamie2703 Lupus 3 09-30-2006 08:12 AM




Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is Off
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off




Join Our Newsletter

Stay healthy through tips curated by our health experts.

Whoops,

There was a problem adding your email Try again

Thank You

Your email has been added








TOP THANKED CONTRIBUTORS



VeeJ (172), ladybud (43), AngelicBrat (16), luca689 (7), ksp (6), neveragain444 (6), luvinmusiq (5), Daisygrace (4), brooklyngirl (4), paperbgprinces (3)

Site Wide Totals

teteri66 (1166), MSJayhawk (1000), Apollo123 (898), Titchou (833), janewhite1 (823), Gabriel (758), ladybud (747), sammy64 (668), midwest1 (665), BlueSkies14 (610)



All times are GMT -7. The time now is 02:20 PM.



Site owned and operated by HealthBoards.comô
Terms of Use © 1998-2014 HealthBoards.comô All rights reserved.
Do not copy or redistribute in any form!