It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Lupus Message Board
Post New Thread   Closed Thread
LinkBack Thread Tools
Old 04-19-2009, 06:28 PM   #1
Senior Member
(female)
 
Join Date: Sep 2004
Posts: 213
Postie HB User
Vasculitis

Is Lupus a vasculitis disease? If vasculitis is ruled out, can a person still have lupus?

If a sed rate is 30, could that be a possibility to go along with vasculitis?

CindyLou

 
Sponsors Lightbulb
   
Old 04-19-2009, 07:35 PM   #2
Member
(female)
 
Join Date: Apr 2009
Location: BC, Canada
Posts: 71
surreygal HB User
Re: Vasculitis

Quote:
Originally Posted by Postie View Post
Is Lupus a vasculitis disease? If vasculitis is ruled out, can a person still have lupus?

If a sed rate is 30, could that be a possibility to go along with vasculitis?

CindyLou
Hi there:
SLE, Systemic Lupus Erythematosis, is actually considered a connective tissue, auto-immune disease. This means a rogue anti-body, rather than dying off and being excreted once it's role of "warrior" has been completed, instead goes forth and attacks healthy tissue/organs, in this case the target is connective tissue. Connective tissue constitutes a wide range of tissue--all organs use it, as does skin, cartilage, muscle, etc. Vasculitis can be a complication for Lupus, because blood vessels are composed of connective tissue. I don't know about sed rate values regarding Lupus--sorry I can't help you there. Take care and best wishes.

 
Sponsors Lightbulb
   
Old 04-19-2009, 08:13 PM   #3
Senior Member
(female)
 
Join Date: Sep 2004
Posts: 213
Postie HB User
Re: Vasculitis

What are symptoms of vasculitis and I know different symptoms of lupus. So what would be the difference.

If a person has a rash on the face and the rheumy said it's a connective tissue disease and not rosacea. Does that rule out vasculitis?

I'm not familiar with vasculitis.

CindyLou

 
Old 04-20-2009, 04:33 PM   #4
Member
(female)
 
Join Date: Mar 2009
Posts: 99
*erica* HB User
Re: Vasculitis

Hi CindyLou,
Lupus is not a vasculitis disease, it is an autoimmune disease. And yes if vasculitis is ruled out a person can still have lupus. Lupus and vasulitis are completely seperate diseases, in some cases vasculitis is caused by an autoimmune disease like lupus and other times vasculitis happens in normally healthy people and has no known cause. Also, measuring your sed rate is a way of helping reach a vasculitis diagnosis. It is an older method of testing and is not specific enough to diagnose vasculitis as opposed to an autoimmune condition like lupus. There are other tests for vasculitis that are much more accurate and specific. I hope this helped and have a nice day
-Erica

 
Old 04-20-2009, 04:58 PM   #5
Senior Member
(female)
 
Join Date: Sep 2004
Posts: 213
Postie HB User
Re: Vasculitis

Hi Erica,

I go to my rheumy tomorrow so it will be interesting to hear what he has to say. The reason I'm asking about vasculitis is because the hematologist I saw in January said I definitely don't have vasculitis. But my CFS doc told me yesterday that when I go to the rheumatologist that he will probably check for vasculitis and other diseases like that.

My sed rate is 30 and out of 11 years I have never had one like that. Mine has always been around a 4 or way under 20. So this is very unusual.

Then last year my rheumy said the rash is definitely a connective tissue disease rash. So I have doc's saying everything.

With a sed rate of 30, can that be vasculitis or lupus? Or is that too low?

CindyLou

 
Old 04-20-2009, 05:52 PM   #6
Member
(female)
 
Join Date: Mar 2009
Posts: 99
*erica* HB User
Re: Vasculitis

Hi CindyLou,
A sed rate of 30 could be vasculitis or lupus or actually a number of different things. Basically your sed rate means you have inflammation, not an extreme amount at 30, but still it is there which means it could be lupus, vasculitis, etc. The symptoms of vasculitis are very similar to those of lupus like fever, fatigue, weight loss, joint pain, etc. However with a rash that was identified as a connective tissue disease rash I would say that it's not vasculitis. Vasculitis can present rashes but they are definatly not CTD rashes and are usually presented on the legs and are either purplish red spots or hyperpigmentation and can be felt with your fingertips.
-Erica

 
Old 04-20-2009, 05:58 PM   #7
Senior Member
(female)
 
Join Date: Sep 2004
Posts: 213
Postie HB User
Re: Vasculitis

Hi Erica:

I just want to thankyou so much for your posts. They are really helping me tremendously to understand these things that I know nothing about. Thanks so much for your great support and it means the world to me.
I would say I don't have vasculitis then definitely. The hematologist looked at my hands and everything when I saw in January and he said I don't have that. I don't have spots or other rashes on legs or arms or nothing.

The rash is on my face and neck. I'm going to ask the rheumy how he knows it's a connective tissue rash. Do you know how they can tell when they look at it?

CindyLou

 
Old 04-20-2009, 06:15 PM   #8
Member
(female)
 
Join Date: Mar 2009
Posts: 99
*erica* HB User
Re: Vasculitis

Hi CindyLou,
It's no problem at all I'm glad you've found some comfort and support through my replies, after all that's what we're all here for
As far as the connective tissue disease rash, there is no way to difinitively diagnose it as a CTD rash by just looking at it. It can be inferred that it is one if it is the malar (butterfly) rash or if the rash happened after exposure to sunlight and then you wouldn't need a skin biopsy which is rather invasive. But the only way you can get a firm diagnosis on the rash would be by having the biopsy done.
-Erica

 
Old 04-20-2009, 06:26 PM   #9
Senior Member
(female)
 
Join Date: Sep 2004
Posts: 213
Postie HB User
Re: Vasculitis

Hi Erica:

If I am in the sun, my rash gets really, really bad within 5 minutes. But when I went to my rheumy last year I asked him if the rash looks more rosacea or malar rash. He said it points more toward lupus rash than rosacea.

CindyLou

 
Old 04-20-2009, 06:35 PM   #10
Member
(female)
 
Join Date: Mar 2009
Posts: 99
*erica* HB User
Re: Vasculitis

CindyLou,
It sounds like your doctor knows what he's doing. If your rash looks like a malar rash and gets worse in the sun it's most likely definatly a CTD rash. Has your doctor given you any inclination that you're getting closer to a diagnosis? I sure hope so, the waiting was always the worst part for me.
-Erica

 
Old 04-20-2009, 06:38 PM   #11
Junior Member
(male)
 
Join Date: Feb 2009
Location: Colorado
Posts: 21
oldcarman HB User
Re: Vasculitis

From my research i have to agree, it is non-vasculitic. Although it does seem that this is not conclusive. Some studies have found evidence to the contrary. I have primarily been looking into neuropsychiatric or CNS Lupus. It seems possible that may be the same things as Hashimoto's encephalopathy. Both of these disease have very similar symptoms. They along with stiffman syndrome and sjogren's are increasingly listed under the umbrella term non-vasculitic autoimmune inflammatory meningoencephalitis.

 
Old 04-20-2009, 06:58 PM   #12
Senior Member
(female)
 
Join Date: Sep 2004
Posts: 213
Postie HB User
Re: Vasculitis

Erica:

I think tomorrow he will be able to get a better picture of what is happening. My doctor faxed over my labwork to him that I just had done last week. He's concerned with my low neutrophil count because it was under last time at 0.5 in November and it's 0.9 and normal is 1.8. So that's still going to be a concern to him. Of course my white count is always low.

Now all of a sudden the sed rate jumped to 30 which never happened before. Also what's really strange is for the past two labs from last November and this month the ANA patternjust shows Nucleolar. All the other years it always showed two patterns. It was always speckled and homogenous. But my ANA is always 320 and now it just shows one pattern.

CindyLou

 
Old 04-21-2009, 04:40 AM   #13
Facilitator
(female)
 
Join Date: Feb 2004
Posts: 5,065
VeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB User
Re: Vasculitis

Postie, hi. Like the others, I also understand that lupus & vasculitis (blood vessel inflammation) are two different conditions. I think ANCA blood test & angiograms are done if systemic vasculitis is suspected.

There's a mild form of vasculitis called "cutaneous vasculitis", not considered dangerous unless skin breaks down. I have some on both ankles that burns & tingles, esp. in hot shower. I check that skin regularly, is all.

Re: lupus rashes, I had deep-punch biopsies done by dermatologists & dermatopathologists. The punch is examined microscopically for immune complex deposits along the dermal/epidermal junction. As a second step, immune stain tests can next be performed on the punch, because lupus rashes often (but not always) fluoresce in these tests, in a way that's seen ONLY in lupus rashes. I was a good candidate for deep-punch, because my rashes were on upper arms & torso. I don't know if deep-punches are done on *facial* rashes, due to needing skin with "depth" & also because the test leaves a scar.

Hope this helps some. Did you get any further ahead yesterday? I hope so! Best wishes, Vee

 
Old 04-21-2009, 03:59 PM   #14
Member
(female)
 
Join Date: Mar 2009
Posts: 99
*erica* HB User
Re: Vasculitis

Hi CindyLou,
It's very strange to me that you ANA patterns changed. As I'm sure you may know speckled and homogenous patterns are almost always indicative of lupus. Homogenous ANA is most closely associated with lupus, discoid lupus, autoimmune hepatitis, and rheumatoid arthritis while speckled patterns are associated with lupus, scleroderma, and sjogren's syndrome. However Nucleolar is usually associated with extensive scleroderma, polymyositis/scleroderma overlap syndrome, and primary pulmonary hypertension. I've never heard of an ANA pattern changing before. I would ask your doctor about that and if you get an answer about it I'd love to learn about it. I wish you all the best
-Erica

 
Old 04-21-2009, 04:07 PM   #15
Senior Member
(female)
 
Join Date: Sep 2004
Posts: 213
Postie HB User
Re: Vasculitis

Hi Erica:

I went to the rheumy today and I have a diagnosis of lupus.

It's very strange that after 10 years, my ANA pattern would automatically change to just one pattern both times I have labwork. It stayed nucleolar. Even though I have nothing of scleroderma so that's the weird part. But people have said also that with nucleolar pattern it can also be lupus.

Also I definitely do not have vasculitis.

CindyLou

 
Closed Thread

Similar Threads
Thread Thread Starter Board Replies Last Post
Vasculitis? Pleurisy? Is this very serious? kinikki Lupus 9 12-02-2010 07:53 PM
vasculitis bill1290 Blood and Blood Vessel 5 04-20-2009 09:13 PM
Brain Bleed - Central Nervous System Vasculitis caroljean Brain & Nervous System Disorders 1 08-21-2008 07:32 AM
Vasculitis or MS or what? topsy123 Multiple Sclerosis 3 12-13-2007 03:03 AM
Lupus and Vasculitis emcreative Lupus 16 11-21-2007 11:41 PM




Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is Off
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off




Sign Up Today!

Ask our community of thousands of members your health questions, and learn from others experiences. Join the conversation!

I want my free account

All times are GMT -7. The time now is 02:02 AM.



Site owned and operated by HealthBoards.comô
Terms of Use © 1998-2014 HealthBoards.comô All rights reserved.
Do not copy or redistribute in any form!