That can be part of the Lupus and medication problem.
Once you start taking any of the meds. you often find
it takes more and more to keep you in check. It's best
to read as much as you can about other things you can
do other than medications. Unless, you have a dangerous
organ involvement these can be helpful. Diet, Vitamins,
biofeedback, relaxation tapes , visualization and lots
of rest. The immune system can be very responsive to
our mind. Just think how easy it is to get a cold when
we are feeling down or how a death of a spouse can
break down the immune system and one dies from what
we call a broken heart.