Why did he want you to cut back? WEre you having problems with it? If not and he hasn't given you a good reason to cut back, I'd go back to 400. Plaq is pretty safe with the exception of the potential eye problems which are rare and shouldn't be a problem if you get your eye exam every 6 mos. Another thing you could do is for a week take 2 /day, the next take 1 one day, 2 the next, 1 the next, etc.