I just started Plaquenil (400 mg a day) two week ago and I started feeling less achy and tired a few days ago. Is it possible for it to work quicker in some people? I've heard it can take months, but I must say that I haven't felt like this since I was a kid - not achy or stiff. Has anyone had a similar experience with Plaquenil? Thank you.
Just an FYI-
Plaquenil is NOT known to start working that fast. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt.
This is the case with everyone I know that takes it. My rheumy has said(and everything I've read on Plaquenil) that Plaquenil NEEDS that amount of time to build in your system before it stats to have beneficial effects.
Any 'feeling good' that early on is most likely due to something else in your body at the time. Maybe a slight remission or just having good days.
It can also be a case of 'mind over matter' which isn't a bad thing! lol
I know it took about 5 mths. for me before it started working.
I haven't been here for a while - just checked in and found this question on Plaquenil - for me it took approx nine weeks to begin to work - I'm only taking 200mg per day so far - it seemed to stop working a few weeks later - most days are pretty good (I s'pose) but I drop nearly every afternoon. I have experimented with different times of the day to take the Plaquenil as it seems to interfere with my sleep, not sure if anyone else has experienced this?
I'm trying Melatonin for my insomnia!
I think my body prefers night time 'cos there's no sun!!
I have been on Plaquenil for about six weeks. The first week was hell as I got used to the medicine -- I was terribly irritable, in a lot of pain, and just not pleasant to be around. After that first week, I felt good for the next three or four weeks. Still a little pain, but better than it was before I started to take the medicine.
Now, I'm in week six and I again have the joint pain, joint stiffness and fatigue. My theory is that I felt good for the first few weeks because of a placibo effect and it's going to take a couple more weeks before I actually feel better because of the chemical effects of the medicine.
But in reality, whether it really takes eight weeks or two weeks, whether it's really the medicine or just the placibo effect, the bottom line is that if you feel better taking it, that's what is important.
Hi, everyone. I felt better a few weeks after starting the Plaquenil. BUT I'd stopped doing sun months prior... When I started I was rash-free but constitutionally miserable (arthritis, swollen joints, low-grade fever, etc.)
The first things to go away were the fever and stiffness (esp. the lower back misery) and the fatigue started lessening quickly. I could stand upright!
I got a couple of "wanna-be" rashes, like ghosts, in lesser form.
Then about 10 weeks in, I had my worst shoulder and elbow pain ever. Nauseating. Lasted three days---almost like my body was doing a computer-style "system dump". Since then, I still get the shoulder & elbow pain, but not that ugly stuff so bad you just hunker down and try not to move.
It might affect us all differently, depending on how much "immune junk" build-up we had at the point of starting the med; how deep our symptoms are; etc. Must be a whole lot of variables... My best to you all, from Vee
I have a question. What if I started Plaquenil, BUT what if I don't really have Lupus (if my face rash is rosacea and my joint pain is something else)...it just concerns me...since there is no definate test for Lupus...so, what if I were to start taking it...would it harm me?
I'm not sure if this is why, but it's been about 13 months ago that I started Plaquenil and I think it's doing some good. ORdinqarily I would be uppiing the Prednisone. I'm only on 10mg and that is good. By the way, I do feel good and exercise now about 5 days a week. Lordy, I'm really working it. Gotta keep that blood moving so my brain gets oxygen to work properly cause I'm forgetting things so much lately. LOL We'll see.
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