Re: High ANA titer with Vitiligo?
Hi. First off, obviously I'm only a patient, so please read in that light, OK? The info I've read correlates vitiligo with a few autoimmunes: pernicious anemia, thyroid conditions, Addison's, etc. Interestingly, lupus doesn't isn't listed...
If lupus IS being considered as a possibility, a rheumatologist looks for the diagnostic criteria & symptoms listed on the "sticky posts" (= permanent info posts) at the top of the thread list. These describe full-blown *systemic* lupus (SLE). In contrast, in "cutaneous lupus", people only meet a few mild criteria, like skin involvement, pain & fatigue.
ANA is only a "theshold test"; in & of itself, it doesn't diagnose anything. PLUS, it may even elevate simply due to a passing virus, a family tendency, etc. Because it is positive in many conditions (incl. multiple rheumatologicial & other specialties as well), it's likely your rheumie will run additional autoimmune panels to look for autoantibodies associated with lupus (while there are many, only several are considered very "specific"). Take a lifetime medical history. Maybe call for a deep-punch skin biopsy, to confirm your depigmentation is due to vitiligo vs. one of the lupus rashes that also can depigment vs. something else altogether. Etc.
Typically joint pain in lupus affects matching joints simultaneously, e.g., both knees, both wrists, etc.
Main thing is not to worry too much until you know more. If it IS lupus (and I hope not), many people remain mild. To read more, see the "sticky" on Resources for recos. Let us know how you make out, OK? Meanwhile, sending best wishes, sincerely, Vee
Last edited by VeeJ; 09-29-2009 at 04:49 AM.
Reason: added sentence