+ ANA, +SM AB titer eGFR 51??? What does this all mean?
Help. I have a hand full of labs that am in need of explaining. Do I have lupus??? Sorry about the spelling
My ANA positive 1:2560
SM AB titer positive 1:360
sgot ast 87
Cardiolipin IGG AB 19 low positive
CARDIOLIPIN IGM AB 16 low positive
MICROSOMAL AB EQUIV'L
SJOGRENS A/SSAAB 1.1 POSITIVE
THYROGLOBULIN AB NEG
DNA AB NATIVE 18 NORMAL RANGE
LUPUS ANTICOAGULANT EVALUATION
TCT 15.6 LOW
CPK 860, to 1600within a few days, back down to 820.
I was diagnosed with Hysimotos thyroiditis about 15 yrs ago, 3 months ago my TSH was within the normal range, but sky rocketed to 160 a few weeks back.
Within the last 2 or so months I have started gaining weight, feeling bloated, forgetful, joint aches and pains, feet and thumb skin hardening, facial edema, abd pain, shortness of breath, extreme muscle weakness in the upper legs, and arms. My Dr checked my Vitamin D which was low, placed me on 50,000mg supplements once a week, re checked my labs for that after 8 weeks and they were lower than when I started the supplements.
I have been to a cardiologist, endocrinologist, rheumetologist, gastroenterologist. The Rheumetologist ordered the above labs but will not return my calls to review the results. I know with the holidays all are busy, but I am just wondering what is going on, and what all the lab results mean. I signed a release to get my labs and have been going over internet style the results. There are to many questions.
My liver ultrasound report said my liver is extremely dense.
CT abd/Pevlis was basically neg except for a fatty liver, and athrosclerosis of the abd aorta
I have atelectisis in both lung bases. I am way to young to have all these symptoms.
The GI Dr thought my body was not absorbing the synthroid or vitamin D.
The Endocrin Dr put me on 2.0 synthroid and 5mcg of cytomel which seems to be helping and the Rheumotoligist put me on 20mg of predisone.
So many questions????? If I do have lupus do I get liver biopsies to check for muscle damage? Can it all be related to the thyroid and I don't have lupus?
Any comments would be greatly appreciated. The waiting is drivng me crazy!
Way too complicated for me to interpret. I'd put a call into the doctor every day until he talked with you. You need to take charge of your medical care. Or gather up all your labs/reports and find a research center/teaching hospital and get an appointment there. You need to see someone who can put all the different tests/symptoms into a package. Autoimmune diseases overlap to a great degree so look for someone who is curious.
I heard from the Dr office today and they told me to take an aspirin a day for my clotting disorder, said my ANA was high because I have arthritis in my hands. I didn't have lupus and that the sjorgens that came back positive is just dry eyes and mouth. I
asked about the smooth muscle titer being elevated and she didnt know what to say. I told her that I didn't think she was looking at the whole picture and that I would wait until Monday to talk to the Dr who has been out of town and probably never reviewed my labs.
Madeleen, hi. I'm sorry for the confusion you're caught up in! I think most of us here can identify with it. I'm with Heidi: you need a *professional* to interpret your labs. But that said, you can read. Have you seen the "stickies" = permanent info posts at the top of the thread list? They contain good reading resources.
I'm only a patient, of course. But in your shoes, I'd want clear statements on multiple things, when your dr. returns. For example: I personally think that whoever it was who "explained" that your ANA is positive because you have "arthritis in your hands" can't possibly be an expert.
Also, I believe SSA & SSB may be positive in lupus *or* Sjogren's. Thus further evaluation is warranted, to determine if you have one, the other, or BOTH. Further, Sjogren's isn't "just" dry mouth & eyes. It's a rheumatic condition that requires monitoring & treatment, just like lupus.
I don't know what "SM" stands for in your labs. Smooth muscle? Anti-Smith? You should ask what it means & what it signifies.
I hope you get clarity SOON, and whatever help is indicated. I also hope you keep posting, as we're good company & understand what it's like to go thru this. Hang tough, OK? Warmest wishes, Vee
(P.S. I had problems for decades before being Dx'ed with lupus. I'm in a tiny subset of lupus, positive SSA, but ANA-negative. What a mess that was! I finally went to a teaching hospital rheumie & got answers quickly, after decades of striking out with many local specialists. They were DUFUSES. Is that a real word? It's the plural of "dufus"! So you just keep trying, OK? OK! Hugs to you!)
Last edited by VeeJ; 12-28-2009 at 06:43 PM.
SM AB is smooth muscle AB which with a Positive ANA could be autoimmune hepatitis. I have been reading alot and trying to understand. Just don't want to over analyze and think I have things I don't. I am concerned that people aren't looking at the whole picture. I appreciate all the your comments and help. I have looked at the stickies and will keep reading!
I have a question about the rash. I dont have the butterfly rash on my face, just when I put lotion on my face now it gets pretty red in a butterfly pattern but fades after an hour or so.
I do get red raised bumps on my feet and knees when I am in the son and this last summer one of the area's stayed dark where the rash was. My symptoms are so vague so I am not sure if a lumpus diagnosis is what I have. I do have the positive ana 1:2560
osteoarthritis, GI/IBS problems, reactive airway disease,the rash from the sun, memory problems. So much of this either could be rel;ated or just coincidence. I was just diagnosed with the clotting disorder ASL (???)and was put on a baby aspirin. Anyway...tomorrow I see the rheumy and maybe some more answers. I just want my thyroid to be normal and to feel better again at this point! Wish me luck!
Your history sounds very much like mine. I had a multinodular goiter, which resulted in a thyroidectomy. I also have hepatitis C, Lupus, RA, OA, fibromyalgia, have had a stroke and mild heart attack. Lupus causes the bodies' own immune system to attack itself. I am a RN, but had to quit work due to my disabilities. On good days, most people don't even know I am sick. But, then there are the days I cannot get out of bed! I don't know if I am helping you or not. My intent is to let you know, you are not alone.