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Old 03-21-2012, 04:41 PM   #1
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Join Date: Mar 2012
Location: ga
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klmcrory HB User
Lupus?

I have Graves Disease and after radi**ion and 3 years l**er I have it under control but....** a recent follow up I told my DR about the joint pain I have been having. He ran some test and will be sending me to a Rheum**ologist.

My test read

Antichrom**in Antibodies 2.5 (high)
RNP Antibodies >8 (high)
ANA positive
Vitamin D is also low
Does this mean Lupus?

Any feed back would be helpful.

Last edited by klmcrory; 03-21-2012 at 04:43 PM.

 
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Old 03-24-2012, 03:31 AM   #2
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VeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB UserVeeJ HB User
Re: Lupus?

Kim, hi. I'm just a patient, but here's how I understand the SLE diagnostic criteria (see "sticky post" at top of thread list). You generally must meet 4 or more, over time, meaning not necessarily simultaneously. During your upcoming appointment, you should literally be able to see the doctor starting his count, thru questions, add'l labs etc.

The two autoantibodies most specific to lupus are anti-ds-DNA and anti-Sm. But I think anti-RNP can be seen in SLE... also in MCTD (mixed connective tissue disease), too. I don't know if it's seen in anything else (sorry).

I think anti-chromatin is considered a kidney marker for SLE, but I don't know it it's considered "specific" to SLE, nor how reliable the test is, nor at what level add'l tests are indicated.

I believe Vitamin D is often low in people with inflammatory conditions, also in people who avoid sun. (Mine tanked last fall, but has improved a lot since I started taking Vitamin D-3 OTC supplements.)

ANA isn't specific to any sincle condition, so it's considered a "threshhold test", meaning if elevated, more specific tests are indicated. (It can also elevate due to a passing virus, family tendency, etc.)

Above aren't answers, more like questions you could add to your list to ask & discuss. When do you go? Good luck! Sincerely, Vee

Last edited by VeeJ; 03-24-2012 at 03:37 AM. Reason: spelling

 
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