Re: A positive anti ds DNA but my doc says no to lupus
Hi again. I think RF can be positive in both RA and lupus. Also, that it doesn't HAVE to be positive for either (which, for RA, is surprising, isn't it?).
Do you know the reference range for the anti-ds-DNA tests you've had? (Think ranges differ among labs & countries.)
Has he cast a wide net? For example, hypothyroidism can cause joint pain. In the US, thyroid tests typically aren't included in a "panel" and thus must be ordered separately. (My sister is hypothyroid & interestingly she & I shared joint pain, wild fatigue, and hair loss. She gained weight & I lost.)
Did he cast a wide net in the autoimmune ballpark by running OTHER autoantibody tests, not just anti-ds-DNA---like anti-Ro, anti-La, anti-RNP, antiphospholipid, etc.? Although anti-ds-DNA is on the criteria list, there are MANY OTHER autoantibodies possible in lupus. For example, I tested positive for anti-Ro, which is seen in both Sjogren's and lupus, but in Sjogren's, ANA is typically very high, and since mine wasn't, that created a "tilt" to lupus. Lupus-specific rashes proven by skin biopsy sealed my Dx.
Did you read the "alternative criteria" sticky post? Those also would add weight to a doctor who really knows lupus.
To be honest, I doubt that lupus is a disease that can be accurately diagnosed by physical exam---and I don't mean any disrespect toward your doctor. It can be so subtle, and its symptoms overlap so many other conditions; it's truly "the great imitator". Best wishes & bye for now, Vee