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Old 02-14-2008, 08:44 PM   #1
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Join Date: Jan 2008
Location: Georgia
Posts: 19
jason915 HB User
New Test Results - CD57 and WB - advise needed

Just got our IgeneX test results back and a new CD57 test from LCorp for my Wife. I have also already seen the Western Blot band breakdown. Based on what I can conclude is that Lyme is a YES and co-infections are a NO. All feedback is much appreciated as I really don't understand much of the results after the WB results.

Here are the results...


CD57
132. This is up from 112 (August 2007).
---------------------------------------------------------------------
IGG WB - According to Igenex = POSITIVE, CDC = NEGATIVE

30 kDa (+)
**39 kDa (+)
**41 kDa (++)
58 kDa (+)

All other bands were negative.
--------------------------------------------------------------
IGM WB - According to Igenex = NEGATIVE, CDC = NEGATIVE

28 kDa (+)
**31 kDa (IND)
**41 kDa (IND)

All other bands were negative.
--------------------------------------------------------------
IFA, B Burgdorferi G/M/A - <1:40 Titer = NEGATIVE
--------------------------------------------------------------
Lyme Multiplex PCR

Genomic - B burgdorferi = NEGATIVE
Plasmid - B burgdorferi = NEGATIVE
--------------------------------------------------------------
B. Microti Antibody G/M

B. microti, IgM - <1:20 Titer = NEGATIVE
B. microti, IgG - <1:40 Titer = NEGATIVE
--------------------------------------------------------------
HME Panel (monocytic)

Human Monocytic IgM - <1:20 Titer = NEGATIVE
Human Monocytic IgG - <1:40 Titer = NEGATIVE
--------------------------------------------------------------
HGE Panel (granulocytic)

Human Granulocytic IgM - <1:20 Titer = NEGATIVE
Human Granulocytic IgG - <1:40 Titer = NEGATIVE
--------------------------------------------------------------
B. Henselae Antibody G/M

B. henselae IgM - <1.20 Titer = NEGATIVE
B. henselae IgG - <1.40 Titer = NEGATIVE
--------------------------------------------------------------
Babesia Fish (RNA) = NEGATIVE
--------------------------------------------------------------

Last edited by jason915; 02-14-2008 at 08:47 PM.

 
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Old 02-15-2008, 05:59 PM   #2
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Join Date: May 2006
Location: northern virginia
Posts: 292
kwebster HB User
Re: New Test Results - CD57 and WB - advise needed

Jason:
First, I am no expert but here's my stab at the Igenix and CD-57 stuff - from what I know of my own experience.

The IGG results indicate an old infection. While Igenix says it is positive for some type of Lyme exposure it does not meet CDC clinical significance. However, most doctors will treat according to symptoms. The CDC stuff is what most illiterate doctors stand by. Cruel as it may sound, many of the people on this board suffer greatly and pay a lot of money because doctors don't recognize Lyme as a terrible disease - that's a topic for another day.

From what my LLMD has told me positive results in the IGM tests indicate a recent exposure. The IND results can be explained if you read the Igenix printout. It indicates there may be something there but, not strong enough to make a determination at this time. According to Igenix samples your wife meets the criteria for a latent infection - it appears.

The CD-57 determines immune function. It doesn't exactly tell you if you have Lyme, but most people who have Lyme have decreased immune function thus the results for the CD-57 will fall in the lower range. For instance. My LLMD said that average results fall between 60-120 with normal funtion. Lyme patients typically fall below the 60 level. It is a good indicator Lyme is present and can determine to some degree if treatment is working. However, other diseases could be at play, like Epstein Barr or CMV. My initial CD-57 was 30 and after three months of abx moved up to 42. Your wifes numbers are 132. Depending on how your doctor interprets this - they may tell her her immune function is ok.

How does she feel??? Again, I am no doctor and there are many more people on this board much more knowledable than I. I can only speak from my recent experience and the lab work I have had done.

Hope this helps!

Kathy

 
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